Results 61 to 70 of about 5,954,666 (293)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
c-Continuous polynomials on l1
Extracta MathematicaeIn this article we study the n-homogeneous polynomials P that are c-continuous on bounded subsets of l1 . We show that P can be decomposed in the form R + Q, where Q and R are n-homogeneous polynomials, with R weakly star continuous and Q (x) = 0 for all
Humberto D. Carrión
doaj +1 more source
Nanomaterials, 2018 The dual-mode emission and multicolor outputs in the time domain from core-shell microcrystals are presented. The core-shell microcrystals, with NaYF4:Yb/Er as the core and NaYF4:Ce/Tb/Eu as the shell, were successfully fabricated by employing the ...
Dandan Ju +8 more
doaj +1 more source
Giant enhancement of THz-frequency optical nonlinearity by phonon polariton in ionic crystals
Nature Communications, 2021 Optical nonlinearity in the THz range is of interest for scientific applications. Here the authors show that THz nonlinearity in ionic crystals can be enhanced by orders of magnitude through phonon polaritons, which is also described by nonlinear ...
Yao Lu +5 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
, 2016 Based on the novel notion of `weakly counital fusion morphism', regular weak multiplier bimonoids in braided monoidal categories are introduced.
Böhm, Gabriella +2 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
, 1998 We examine the consequences of classical ergodicity for the localization properties of individual quantum eigenstates in the classical limit. We note that the well known Schnirelman result is a weaker form of quantum ergodicity than the one implied by ...
Heller, E. J., Kaplan, L.
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Optical clearing and shielding with fan-shaped vortex beams
APL Photonics, 2020 We propose and demonstrate a new method for creation of fan-shaped optical vortex beams by rational phase modulation and assembly based on a well-known conical vortex phase.
Haiping Wang +8 more
doaj +1 more source