Results 31 to 40 of about 208,031 (261)

Layer-by-Layer Printing of Photopolymers in 3D: How Weak is the Interface? [PDF]

open access: yesACS Applied Materials & Interfaces, 2020
Additive manufacturing or, as also called, three-dimensional (3D) printing is considered as a game-changer in replacing traditional processing methods in numerous applications; yet, it has one intrinsic potential weakness related to bonding of layers formed during the printing process. Prior to finding solutions for improvement, a thorough quantitative
H. Gojzewski   +6 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Weak double layers in the auroral ionosphere

open access: yesLaser and Particle Beams, 1987
Previous work on the evolution of weak double layers in a hydrogen plasma has been extended to include H+ and O+ with relative drift. It has been shown (Bergmann & Lotko 1986) that the relative drift between hydrogen and oxygen ions due to a quasistatic parallel electric field gives rise to a strong linear fluid instability which dominates the ion ...
M. K. Hudson   +3 more
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Modeling of crack propagation in weak snowpack layers using the discrete element method [PDF]

open access: yesThe Cryosphere, 2015
Dry-snow slab avalanches are generally caused by a sequence of fracture processes including (1) failure initiation in a weak snow layer underlying a cohesive slab, (2) crack propagation within the weak layer and (3) tensile fracture through the slab ...
J. Gaume   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Dynamic Responses of Concrete-Face Rockfill Dam to Different Site Conditions under Near-Fault Earthquake Excitation

open access: yesBuildings, 2023
The western region of China is rich in hydropower resources and characterized by unique geological conditions. For the construction or planned construction of high dams in this region, different types of cover layers are formed due to special geological ...
Mengdie Zhao   +3 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Stress Concentrations in Weak Snowpack Layers and Conditions for Slab Avalanche Release

open access: yesGeophysical Research Letters, 2018
Dry‐snow slab avalanches release due to the formation of a crack in a weak layer buried below cohesive snow slabs, followed by rapid crack propagation.
J. Gaume   +3 more
doaj   +1 more source

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