Results 81 to 90 of about 10,780,423 (379)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Electronic Journal of Differential Equations, 2017 In this work, we are interested in the mathematical model of reaction diffusion systems. The originality of our study is to work with concentrations appearing in reactors together with measure initial data.
Nour Eddine Alaa, Fatima Aqel
doaj
Weak solutions for weak turbulence models in electrostatic plasmas
, 2023 The weak turbulence model, also known as the quasilinear theory in plasma physics, has been a cornerstone in modeling resonant particle-wave interactions in plasmas. This reduced model stems from the Vlasov-Poisson/Maxwell system under the weak turbulence assumption, incorporating the random phase approximation and ergodicity.
Huang, Kun, Gamba, Irene M.
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2019 To verify the solution of a typical Crocco boundary problem, a numerical experiment was performed using an implicit second-order difference scheme. It is shown that a numerical solution approximates a weak solution of a typical Crocco limit problem ...
Petrichenko Mikhail, Kotov Eugene
doaj +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Nonexistence of solutions results for certain fractional differential equations
Mathematical Modelling and Analysis, 2011 This paper is meant to establish sufficient conditions for the nonexistence of weak solutions to nonlinear fractional diffusion equation in space and time with nonlinear convective term. The Fujita exponent is determined.
Mohamed Berbiche
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Weak solutions for p-Laplacian equation
Advances in Nonlinear Analysis, 2012 In this work we consider the p-Laplacian type parabolic equation with Dirichlet boundary condition and establish the existence of weak solutions using Leray–Schauder's fixed point theorem and semi-discretization process.
Bhuvaneswari Venkatasubramaniam +2 more
doaj +1 more source