Results 91 to 100 of about 1,691,019 (337)
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Weighted function spaces of fractional derivatives for vector fields
Electronic Journal of Differential Equations, 2007 We introduce and study weighted function spaces for vector fields from the point of view of the regularity theory for quasilinear subelliptic PDEs.
Andras Domokos
doaj
On the regularity of weak solutions to $H$-systems
Rendiconti Lincei, Matematica e Applicazioni, 2007 In this paper we prove that every weak solution to the H -surface equation is locally bounded, provided the prescribed mean curvature H satisfies a suitable ...
openaire +5 more sources
FEBS Open Bio, EarlyView.Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu +8 more
wiley +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
FEBS Open Bio, EarlyView.We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Determining Projections and Functionals for Weak Solutions of the Navier-Stokes Equations
, 2010 In this paper we prove that an operator which projects weak solutions of the two- or three-dimensional Navier-Stokes equations onto a finite-dimensional space is determining if it annihilates the difference of two "nearby" weak solutions asymptotically ...
Holst, Michael, Titi, Edriss
core
Some recent results on the existence of global-in-time weak solutions to the Navier-Stokes equations of a general barotropic fluid [PDF]
, 2002 Eduard Feireisl
openalex +1 more source
FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The Poisson equation from non-local to local
Electronic Journal of Differential Equations, 2018 We analyze the limiting behavior as $s\to 1^-$ of the solution to the fractional Poisson equation $(-\Delta)^s{u_s}=f_s$, $x\in\Omega$ with homogeneous Dirichlet boundary conditions $u_s\equiv 0$, $x\in\Omega^c$. We show that $\lim_{s\to 1^-} u_s =u$,
Umberto Biccari +1 more
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