Results 91 to 100 of about 634,419 (341)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

A nonlinear wave equation with a nonlinear integral equation involving the boundary value

open access: yesElectronic Journal of Differential Equations, 2004
We consider the initial-boundary value problem for the nonlinear wave equation $$displaylines{ u_{tt}-u_{xx}+f(u,u_{t})=0,quad xin Omega =(0,1 ...
Thanh Long Nguyen, Tien Dung Bui
doaj  

Weak solutions for weak turbulence models in electrostatic plasmas

open access: yes, 2023
The weak turbulence model, also known as the quasilinear theory in plasma physics, has been a cornerstone in modeling resonant particle-wave interactions in plasmas. This reduced model stems from the Vlasov-Poisson/Maxwell system under the weak turbulence assumption, incorporating the random phase approximation and ergodicity.
Huang, Kun, Gamba, Irene M.
openaire   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Existence of solutions for quasilinear elliptic degenerate systems with L^1 data and nonlinearity in the gradient

open access: yesElectronic Journal of Differential Equations, 2013
In this article we show the existence of weak solutions for some quasilinear degenerate elliptic systems arising in modeling chemotaxis and angiogenesis.
Abdelhaq Mouida   +3 more
doaj  

The existence and uniqueness of global admissible conservative weak solution for the periodic single-cycle pulse equation [PDF]

open access: yesarXiv, 2020
This paper is devoted to the study of the existence and uniqueness of global admissible conservative weak solutions for the periodic single-cycle pulse equation. We first transform the equation into an equivalent semilinear system by introducing a new set of variables.
arxiv  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Scaling-Invariant Serrin Criterion via One Row of the Strain Tensor for the Navier–Stokes Equations

open access: yesMathematics
Miller (Arch. Rational Mech. Anal., 2020) posed the question of whether it is possible to prove the Navier–Stokes regularity criterion using only one entry of the strain tensor Sij.
Juan Du, Fan Wu
doaj   +1 more source

Weak solutions for a nonlinear dispersive equation

open access: yesJournal of Mathematical Analysis and Applications, 1977
AbstractIn this paper we study the existence, uniqueness, and regularity of the solutions for the Cauchy problem for the evolution equation ut + (f (u))x − uxxt = g(x, t), (∗) where u = u(x, t), x is in (0, 1), 0 ⩽ t ⩽ T, T is an arbitrary positive real number,f(s)ϵC1R, and g(x, t)ϵ L∞(0, T; L2(0, 1)).
L.A. Medeiros, M. Milla Miranda
openaire   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

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