Results 91 to 100 of about 11,044,020 (324)
Weak-strong uniqueness of hydrodynamic flow of nematic liquid crystals
Electronic Journal of Differential Equations, 2012 This article concerns a simplified model for a hydrodynamic system of incompressible nematic liquid crystal materials. It is shown that the weak-strong uniqueness holds for the class of weak solutions provided that either $(mathbf{u}, ablamathbf{d ...
Ji-hong Zhao, Qiao Liu
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Weak solutions for a strongly-coupled nonlinear system
Electronic Journal of Differential Equations, 2006 In this paper the authors study the existence of local weak solutions of the strongly nonlinear system $$displaylines{ u''+mathcal{A}u +f(u,v)u = h_1 cr v''+mathcal{A}v +g(u,v)v = h_2 }$$ where $mathcal{A}$ is the pseudo-Laplacian operator and $f$, $g$, $
Osmundo A. Lima +2 more
doaj
On $H^2$ solutions and $z$-weak solutions of the 3D Primitive Equations [PDF]
, 2015 Global in time well-posedness of $H^2$ solutions and $z$-weak solutions of the 3D Primitive equations in a bounded cylindrical domain is proved. More specifically, uniform in time boundedness and bounded absorbing sets are obtained for both $H^2 ...
N. Ju
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Weak solutions for weak turbulence models in electrostatic plasmas
, 2023 The weak turbulence model, also known as the quasilinear theory in plasma physics, has been a cornerstone in modeling resonant particle-wave interactions in plasmas. This reduced model stems from the Vlasov-Poisson/Maxwell system under the weak turbulence assumption, incorporating the random phase approximation and ergodicity.
Huang, Kun, Gamba, Irene M.
openaire +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source