Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan +3 more
wiley +1 more source
The heat exchange tubes in the secondary steam generator of pressurized water reactor vibrate due to the impact of fluid, which results in collision leading to fretting wear. The work-rate can characterize random vibrations over time.
Wenjie Pei +4 more
doaj +1 more source
Prediction of Wear in Crosslinked Polyethylene Unicompartmental Knee Arthroplasty
Wear-related complications remain a major issue after unicompartmental arthroplasty. We used a computational model to predict knee wear generated in vitro under diverse conditions.
Jonathan Netter +5 more
doaj +1 more source
A Study of the Wear Behavior of a Rail Material [PDF]
The rail track is one of the most important elements of a railway system. During the passage of trains, the rails are subjected to contact load that comes from the wheels of the train.
Lucky Ugochukwu Adoh, Samuel Tesfaye
doaj
Wheel material wear mechanisms and transitions [PDF]
In order to develop more durable wheel materials to cope with the new specifications being imposed on wheel wear, a greater understanding is needed of the wear mechanisms and transitions occurring in wheel steels, particularly at higher load and slip ...
Dwyer-Joyce, R.S. +3 more
core
Micro/Nanostructure and tribological characteristics of pressureless sintered carbon nanotubes reinforced aluminium matrix composites [PDF]
This study reports the manufacture, microstructure, and tribological behaviour of carbon nanotube reinforced aluminium composites against pure aluminium. The specimens were fabricated using powder metallurgy method. The nanotubes in weight percentages of
Basu, Sourajyoti +4 more
core +4 more sources
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Dry Sliding Wear Behavior of Super Duplex Stainless Steel AISI 2507: a Statistical Approach
The dry sliding wear behavior of heat-treated super duplex stainless steel AISI 2507 was examined by taking pin-on-disc type of wear-test rig. Independent parameters, namely applied load, sliding distance, and sliding speed, influence mainly the wear ...
Davanageri M. +2 more
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
A comparative analysis of the wear characteristics of glazes generated on the ordinary Portland cement surface of concrete by means of CO2 and high power diode laser radiation [PDF]
The wear characteristics of a glaze generated on the ordinary Portland cement (OPC) surface of concrete using a 2 kW high power diode laser (HPDL) and a 3 kW CO2 laser have been determined.
Borodina +11 more
core +1 more source

