Results 111 to 120 of about 10,965 (175)

DNA replication stress and translational repression converge to drive CDK1- and caspase-dependent apoptosis in Ewing sarcoma. [PDF]

Oncogene
Koppenhafer SL, Thomas MV, Mhindu MT, Zimmerman JAO, Gordon DJ.   +4 more
europepmc   +1 more source

Synthetic lethality in cancer: mechanism exploration and therapeutic applications. [PDF]

Cell Commun Signal
Zhao P, Wang P, Xu T, Chen L, Jia Q, Li M.   +5 more
europepmc   +1 more source

The WEE1 inhibitor azenosertib broadly enhances efficacy of antibody-drug conjugates with topoisomerase I and microtubule inhibitor payloads. [PDF]

iScience
Guo X, Kim D, Harismendy O, Cabrera E, Chung H, Meric-Bernstam F, Lackner MR, Lee C, Ma J.   +8 more
europepmc   +1 more source

Histotype and molecular subtype integration in epithelial ovarian cancer: implications for targeted treatment. [PDF]

Cancer Metastasis Rev
Liu S, Sun C.
europepmc   +1 more source

An overview of the DNA damage response in female reproductive system and breast cancers: A narrative review. [PDF]

Int J Reprod Biomed
Zafari M, Zarei H, Sadeghi E, Lotfi Asrami F, Bahmani F, Jahani S, Maliki DSK, Musavi H, Abdollahi A.   +8 more
europepmc   +1 more source

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review). [PDF]

Oncol Rep
Wang L, Feng Y, Liu Q.
europepmc   +1 more source

Dynamic regulation of origin firing factors links CDK activity to dormant origin activation. [PDF]

Nat Commun
Hossain MS, Sansam CG, Wittig KA, Noble TD, Boyd KA, Sansam CL.   +5 more
europepmc   +1 more source

Structural Studies of βTrCP Reveal Plasticity in Binding Modes of Consensus and Nonconsensus Degrons. [PDF]

ACS Chem Biol
Collie GW, Mak H, Acebrón-García-de-Eulate M, Argyrou A, Couturier M, Cuomo ME, O Donovan DH, Russell IC, Wells G, Winter-Holt J.   +9 more
europepmc   +1 more source

Radiogenomics and the DNA damage response: opportunities for biomarker-guided radiosensitization in pancreatic cancer. [PDF]

Front Oncol
Karam MN, Hajj J, Crane CH, Ramia P, Geara F, Hamadeh N, Scott JG, Grobmyer S, Almond R, O'Reilly EM, Hajj C.   +10 more
europepmc   +1 more source

Ataxia telangiectasia mutated (ATM) kinase as a predictive biomarker in clinical oncology: implications for a precision treatment approach. [PDF]

Neoplasia
Pham AT, Yuan F, Nagathihalli NS, Dosch AR.   +3 more
europepmc   +1 more source