Results 91 to 100 of about 13,336 (197)
Investigation into the stability of WEE1 kinase in plants [PDF]
, 2012 Phosphoregulation is essential for the control of cell division. In yeasts and animals, premature entry into mitosis is prevented by the inhibitory phosphorylation of CDK by WEE1 kinase.
Cook, Gemma S
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Studies on the role of WEE1 in the plant cell cycle [PDF]
WEE 1 is a key eukaryotic cell cycle regulator. In plants it has a clear role at the DNA damage/ DNA replication checkpoints. I aimed to discover the functional significance of interactions between WEE1 and other cellular proteins in ...
Rafiei, Golnaz
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Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Unveiling a new role for Wee1 during S-phase entry
Progression through the cell cycle requires temporal and spatial control of cyclin dependent kinase (CDK) activity. Wee1 kinase and Cdc25 phosphatases play a key role in CDK regulation through inhibitory phosphorylation and activating desphosphorylation ...
Morales, Lucas
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High WEE1 expression is independently linked to poor survival in multiple myeloma
Blood Cancer JournalCurrent prognostic scores in multiple myeloma (MM) currently rely on disease burden and a limited set of genomic alterations. Some studies have suggested gene expression panels may predict clinical outcomes, but none are presently utilized in clinical ...
Anish K. Simhal +8 more
doaj +1 more source
Redundant Ubiquitin Ligase Activities Regulate Wee1 Degradation and Mitotic Entry
, 2007 The irreversible nature of mitotic entry is due to the activation of mitosis specific kinases such as cdk1/cyclin B. Cdk1/cyclin B induces activation of mitosis by promoting phosphatases while suppressing inhibitory factors such as the tyrosine kinase ...
Smith, Anthony +7 more
core +1 more source
Studies on the role of WEE1 in the plant cell cycle [PDF]
, 2012 WEE 1 is a key eukaryotic cell cycle regulator. In plants it has a clear role at the DNA damage/ DNA replication checkpoints. I aimed to discover the functional significance of interactions between WEE1 and other cellular proteins in Arabidopsis thaliana
Rafiei, Golnaz
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Cell cycle regulation of a Xenopus Wee1-like kinase [PDF]
, 1995 Using a polymerase chain reaction-based strategy, we have isolated a gene encoding a Wee1-like kinase from Xenopus eggs. The recombinant Xenopus Wee1 protein efficiently phosphorylates Cdc2 exclusively on Tyr- 15 in a cyclin-dependent manner.
Mueller, Paul R. +2 more
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