Results 81 to 90 of about 10,965 (175)

Selective Macrocyclic WEE1 Kinase Inhibitors with Strong Efficacy against Patient-Derived Colorectal Cancer Organoids. [PDF]

J Med Chem
Syphers JL, Wright JA, Kumar A, To N, Elson L, Krämer A, Müller S, Morasch V, Chang A, Young S, Sloan EK, de Nys R, Silva TN, Vrbanac L, Barratt KR, Leeflang J, Hasan ST, Gable RW, Knapp S, Worthley DL, Mukherjee S, Stockton K, Woods SL, Priebbenow DL, Baell JB.   +24 more
europepmc   +1 more source

3D tissue model to patient atlas: dynamic network topology reveals PDAC chemoresistance bottlenecks. [PDF]

NPJ Syst Biol Appl
Almasi M, Nieves Pereira JG, Dandekar T, Dandekar G, Balkenhol J.   +4 more
europepmc   +1 more source

Combined Inhibition of Wee1 and Checkpoint Kinases Synergistically Provokes S-Phase Progression and Mitotic Entry, and Promotes Cell Death Under Heat Stress. [PDF]

Genes Cells
Muratani T, Takeya H, Ishibashi R, Kurakawa T, Ikushiro SI, Nagai Y, Tabuchi Y, Kondo T, Furusawa Y.   +8 more
europepmc   +1 more source

WEE1 wt Allele [PDF]

, 2020
openaire   +1 more source

G2/M Checkpoint Dependency in High-Grade Serous Tubo-Ovarian Carcinoma: Mechanisms and Therapeutic Implications. [PDF]

Genes (Basel)
Tian Z, McLean K.
europepmc   +1 more source

WEE1 kinase in cancer: Molecular mechanisms and inhibitor insights. [PDF]

EXCLI J
Kumar A, Paudel KR, Kaur R, Bhatia R.
europepmc   +1 more source

Senescence-Associated Checkpoint Gene Dysregulation in Established Osteoarthritis: Integrated Transcriptomic Analysis and In Vitro Evaluation of CDK6 and WEE1. [PDF]

Biomedicines
Liao CS, Ju YC, Wang MX, Long C, Lan FJ.
europepmc   +1 more source

WEE1 kinase inhibitor shows promise [PDF]

Nature Reviews Clinical Oncology, 2019
openaire   +2 more sources

WEE1 Inhibition as a Novel Therapeutic Strategy in Cutaneous T-Cell Lymphoma. [PDF]

Cancers (Basel)
Özistanbullu D, Bahrami K, Doll M, Reichenbach G, Pöschl SM, Wilhelm R, Stege H, Zöller N, Winkler L, Jäger M, Nicolay JP, Quist SR, Kaufmann R, Meissner M, Schilling B, Kleemann J, Cinatl J, Kippenberger S.   +17 more
europepmc   +1 more source

Computational mapping of productive POI-E3 ligase conformations to guide de novo degrader design: application to WEE1 and PKMYT1 PROTACs. [PDF]

J Cheminform
Nassar H, Schmidt M, Ibrahim HS, Robaa D, Sippl W.   +4 more
europepmc   +1 more source