Results 81 to 90 of about 9,531 (127)

Targeting Replicative Stress and DNA Repair by Combining PARP and Wee1 Kinase Inhibitors Is Synergistic in Triple Negative Breast Cancers with Cyclin E or BRCA1 Alteration. [PDF]

Cancers (Basel), 2021
Chen X, Yang D, Carey JPW, Karakas C, Albarracin C, Sahin AA, Arun BK, Guray Durak M, Li M, Kohansal M, Bui TN, Ha MJ, Hunt KK, Keyomarsi K.   +13 more
europepmc   +1 more source

Development and Characterization of a Wee1 Kinase Degrader. [PDF]

Cell Chem Biol, 2020
Li Z, Pinch BJ, Olson CM, Donovan KA, Nowak RP, Mills CE, Scott DA, Doctor ZM, Eleuteri NA, Chung M, Sorger PK, Fischer ES, Gray NS.   +12 more
europepmc   +1 more source

Chemically Induced Degradation of WEE1 Kinase for Difficult to Treat Diseases. [PDF]

ACS Med Chem Lett, 2020
Kargbo RB.
europepmc   +1 more source

WEE1 kinase in cancer: Molecular mechanisms and inhibitor insights. [PDF]

EXCLI J
Kumar A, Paudel KR, Kaur R, Bhatia R.
europepmc   +1 more source

Wee1 Kinase Inhibitor AZD1775 Effectively Sensitizes Esophageal Cancer to Radiotherapy. [PDF]

Clin Cancer Res, 2020
Yang L, Shen C, Pettit CJ, Li T, Hu AJ, Miller ED, Zhang J, Lin SH, Williams TM.   +8 more
europepmc   +1 more source

Selective Macrocyclic WEE1 Kinase Inhibitors with Strong Efficacy against Patient-Derived Colorectal Cancer Organoids. [PDF]

J Med Chem
Syphers JL, Wright JA, Kumar A, To N, Elson L, Krämer A, Müller S, Morasch V, Chang A, Young S, Sloan EK, de Nys R, Silva TN, Vrbanac L, Barratt KR, Leeflang J, Hasan ST, Gable RW, Knapp S, Worthley DL, Mukherjee S, Stockton K, Woods SL, Priebbenow DL, Baell JB.   +24 more
europepmc   +1 more source

Melatonin modulates the gene expression of WEE1 kinase and clock genes: a crosstalk between the molecular clocks of the placenta? [PDF]

Front Endocrinol (Lausanne)
Venegas C, Jara-Medina K, Cueto N, Cabello-Guzmán G, Lagunas C, Lillo L, Valenzuela-Melgarejo FJ.   +6 more
europepmc   +1 more source

Correction: Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia. [PDF]

Cancer Cell Int
Bell HL, Blair HJ, Singh M, Moorman AV, Heidenreich O, van Delft FW, Lunec J, Irving JAE.   +7 more
europepmc   +1 more source

Azenosertib Is a Potent and Selective WEE1 Kinase Inhibitor with Broad Antitumor Activity Across a Range of Solid Tumors. [PDF]

Mol Cancer Ther
Ma J, Liu W, Li J, Kim D, Kim S, Levy A, Cai Z, Bunker KD, Recio-Boiles A, Segar JM, Sen S, Doroshow DB, Jandial D, Rutgard M, Harismendy O, Grant SK, Samatar AA, Fischer KM, Lackner MR.   +18 more
europepmc   +1 more source

Therapeutic potential of targeting the FLNA-regulated Wee1 kinase in adrenocortical carcinomas. [PDF]

Int J Cancer
Esposito E, Marra G, Catalano R, Maioli S, Nozza E, Barbieri AM, Hantel C, Di Dalmazi G, Sigala S, Geginat J, Cassinotti E, Baldari L, Palmieri S, Mangone A, Berruti A, Ferrante E, Mantovani G, Peverelli E.   +17 more
europepmc   +1 more source