Results 91 to 100 of about 166,174,665 (263)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Portrait of Donald Friend, 1987 [picture] /

, 1987
Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference print at P641/2/R.; Also available online at: http://nla.gov.au/nla.pic-an12119208; Exhibited: "Donald Friend: A charmed life", National ...
Weight, Greg, 1946-
core  

The weight-inclusive vs. weight-normative approach to health: Evaluating the evidence for prioritizing well-being over weight [PDF]

, 2014
Using an ethical lens, this review evaluates two methods of working within patient care and public health: the weight-normative approach (emphasis on weight and weight loss when defining health and well-being) and the weight-inclusive approach (emphasis ...
Shuman, E., Chad Davis, Deb Burgard, Annunziato, R.A., Tracy L. Tylka, Tylka, Tracy L., Danielsdottir, S., Rachel A. Annunziato, Davis, C., Sigrún Daníelsdóttir, Burgard, D., Rachel M. Calogero, Calogero, Rachel M., Ellen Shuman   +13 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Portrait of George Gittoes, 1992 [picture] /

, 1992
Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference print at P641/12/R.; Also available online at: http://nla.gov.au/nla.pic ...
Weight, Greg, 1946-
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Extracting Weight of Evidence from p-Value via Bayesian Approach to Activation Likelihood Estimation Meta-Analysis

Brain Sciences
Background: p-values are ubiquitous in scientific research, yet they fundamentally fail to quantify the strength of evidence for or against competing hypotheses. This limitation is particularly problematic in neuroimaging meta-analyses, where researchers
Tommaso Costa, Jordi Manuello, Franco Cauda, Annachiara Crocetta, Donato Liloia   +4 more
doaj   +1 more source

Portrait of Guy Warren, 1992 [picture] /

, 1992
Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference print at P641/14/R.; Also available in electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Weight, Greg, 1946-
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Multi-Influencing Factors Landslide Susceptibility PredictionModel Based on Monte Carlo Neural Network

Tsinghua Science and Technology
Geological hazard risk assessment and severity prediction are of great significance for disaster prevention and mitigation. Traditional methods require a long time to evaluate and rely heavily on human experience.
Hongtao Zhang, Qingguo Zhou
doaj   +1 more source