Results 81 to 90 of about 2,032,974 (307)

Seafloor Stability Assessment of Jiaxie Seamount Group Using the “Weight-of-Evidence” (WoE) Method, Western Pacific Ocean

Journal of Marine Science and Engineering
The deep sea is gradually being exploited, yet research on the stability of the deep seabed is scarce. In this study, the seafloor stability of the Jiaxie Seamount Group in the western Pacific Ocean was assessed using the weight-of-evidence (WoE) method ...
Xuebing Yin, Yongfu Sun, Weikun Xu, Wei Gao, Heshun Wang, Sidi Ruan, Yihui Shao   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

South Asian women’s views and experiences of weight, diet and physical activity changes before, during and after pregnancy [PDF]

, 2013
Being pregnant and becoming a parent is a crucial time when lifestyle behaviours may change and weight gain and retention may occur. This point in the life cycle presents a critical opportunity to advise and support South Asian women, who have a high ...
Brignall, Kathryn
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

What determines weight loss behaviour and body weight satisfaction in Australia? Evidence from the HILDA survey

, 2015
This thesis undertakes an empirical investigation to identify factors that influence the decision to undertake weight loss behaviour using the nationally representative HILDA dataset.
Soldi, Christopher John
core  

PARENTAL INFLUENCES ON CHILD WEIGHT LOSS: PERCEPTION, WILLINGNESS TO CHANGE, AND BARRIERS [PDF]

, 2013
Parents are a primary contributor to the development of obesegenic behavior in youth. However, many parents do not perceive their child’s weight to be a problem, are not ready to make changes, and may be overwhelmed by obstacles to behavior change ...
White, David
core  

Exploring the evidence base for Tier 3 weight management interventions for adults: a systematic review: Multidisciplinary adult weight management [PDF]

, 2017
Specialist weight management services provide a treatment option for severe obesity. The objective of the study is to review the characteristics, impact and practice implications of specialist weight management services for adults in the UK.
O'Malley, Claire, Tedstone, A. E. (Alison), Summerbell, C., Ells, Louisa J, Coulton, V., C. O'Malley, Blackshaw, J, Blackshaw, Jamie, Brown, Tamara J, T. J. Brown, Ells, Louisa, Ells, L.J., Coulton, Vicki, C. Summerbell, Coulton, V, L. J. Ells, V. Coulton, Brown, T.J., J. Blackshaw, Summerbell, C. D. (Carolyn), Summerbell, Carolyn, Brown, Tamara, O'Malley, Claire; id_orcid, Tedstone, A., Tedstone, Alison, O'Malley, C., Blackshaw, J., A. Tedstone   +27 more
core   +1 more source

Advancing Endocrine Disruptors via In Vitro Evaluation: Recognizing the Significance of the Organization for Economic Co-Operation and Development and United States Environmental Protection Agency Guidelines, Embracing New Assessment Methods, and the Urgent Need for a Comprehensive Battery of Tests

Toxics
Efforts are being made globally to improve the evaluation and understanding of endocrine-disrupting chemicals. Recognition of their impact on human health and the environment has stimulated attention and research in this field.
Sophie Fouyet, Marie-Caroline Ferger, Pascale Leproux, Patrice Rat, Mélody Dutot   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source