Results 91 to 100 of about 536,376 (289)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Bluetooth positioning based on weighted K-nearest neighbors and adaptive bandwidth mean shift
Bluetooth positioning is an important and challenging topic in indoor positioning. Although a lot of algorithms have been proposed for this problem, it is still not solved perfectly because of the instable signal strengths of Bluetooth.
Qi Wang +4 more
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Some Tauberian conditions for the weighted mean method of summability [PDF]
Klasik Tauber teorisi, bir toplanabilme metodu tarafından toplanan dizinin yakınsaklığının elde edilmesi için gerekli olan koşulları bulmak üzerine kurulmuştur.
Bolat, Harun
core
This paper proposes a new original non-calculus method to solving the utility maximization problem using the Cobb-Douglas and the CES utility functions, and incorporating the weighted arithmetic-geometric-mean inequality (weighted AM-GM inequality) and ...
Vedran Kojić
doaj +1 more source
Boundary element methods as weighted mean values
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
An equivalent reformulation of summability by weighted mean methods, revisited
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Móricz, Ferenc, Rhoades, Billy E.
openaire +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source

