Results 101 to 110 of about 1,675,186 (285)

Bluetooth positioning based on weighted K-nearest neighbors and adaptive bandwidth mean shift

open access: yesInternational Journal of Distributed Sensor Networks, 2017
Bluetooth positioning is an important and challenging topic in indoor positioning. Although a lot of algorithms have been proposed for this problem, it is still not solved perfectly because of the instable signal strengths of Bluetooth.
Qi Wang   +4 more
doaj   +1 more source

An Adaptive Image Inpainting Method Based on the Weighted Mean

open access: yesInformatica, 2019
Imaging inpainting is the process of digitally filling-in missing pixel values in images and requires carefully crafted image analysis tools. In this work, we propose an adaptive image inpainting method based on the weighted mean. The weighted mean is assessed to be better than the median because, for the case of the weighted mean, we can exclude the ...
Nguyen Hoang Hai   +4 more
openaire   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A non-calculus approach to solving the utility maximization problem using the Cobb-Douglas and CES utility function

open access: yesCroatian Operational Research Review, 2015
This paper proposes a new original non-calculus method to solving the utility maximization problem using the Cobb-Douglas and the CES utility functions, and incorporating the weighted arithmetic-geometric-mean inequality (weighted AM-GM inequality) and ...
Vedran Kojić
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Modified Robust M-approach to estimate the parameters of linear Regression model [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2009
The idea of this research is to find construction Weighted Robust for the estimate parameters of the linear regression model by blend Robust M- approach and Weighted Least Squares method to handle the influence of Outlier Values, which don't harmonies ...
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Improved Confidence-Interval Estimations Using Uncertainty Measure and Weighted Feature Decisions for Cuff-Less Blood-Pressure Measurements

open access: yesBioengineering
This paper presents a method to improve confidence-interval (CI) estimation using individual uncertainty measures and weighted feature decisions for cuff-less blood-pressure (BP) measurement. We obtained uncertainty using Gaussian process regression (GPR)
Soojeong Lee   +2 more
doaj   +1 more source

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