Results 71 to 80 of about 527,119 (255)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On equivalence of absolute double weighted mean methods
Quaestiones Mathematicae, 2020 Bor [1], Bor and Thorpe [2] and the author [8] established the set of necessary and sufficient condition for the equivalence of absolute weighted mean summability methods of innite series. In the present paper we extend their result to doubly innite series by two dimensional weighted mean, which also includes the result of Rhoades [7].
openaire +4 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Geodesy and GeodynamicsShort-term (up to 30 days) predictions of Earth Rotation Parameters (ERPs) such as Polar Motion (PM: PMX and PMY) play an essential role in real-time applications related to high-precision reference frame conversion.
Fei Ye, Yunbin Yuan
doaj +1 more source
Bluetooth positioning based on weighted K-nearest neighbors and adaptive bandwidth mean shift
International Journal of Distributed Sensor Networks, 2017 Bluetooth positioning is an important and challenging topic in indoor positioning. Although a lot of algorithms have been proposed for this problem, it is still not solved perfectly because of the instable signal strengths of Bluetooth.
Qi Wang +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sensors, 2019 Time difference of arrival (TDoA) based on a group of sensor nodes with known locations has been widely used to locate targets. Two-step weighted least squares (TSWLS), constrained weighted least squares (CWLS), and Newton−Raphson (NR) iteration ...
Peng Wu +5 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source