Results 41 to 50 of about 106,969 (295)

AD|ARC (Administrative Data | Agricultural Research Collection): Characteristics of farm households participating in agri-environment schemes in Wales, UK.

International Journal of Population Data Science
Objectives • Describe the sociodemographic and farm business characteristics of farming households in Wales that have agri-environment contracts (voluntarily opting-in) without primary farm subsidies (voluntarily opting-out).
Sian Morrison-Rees, Rachael Loftus, Laura Madden, Freya Pryce, Matthew Curds, Paul Caskie   +5 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Evaluation of the feasibility of 3D scanning to provide individualized compression therapies among healthy volunteer subjects

Veins and Lymphatics, 2018
Not ...
Michael Clark, Sue Hagelstein, Nia Jones
doaj   +1 more source

Networking Historic Environmental Standards to Address Modern Challenges for Sustainable Conservation in HBIM

Applied Sciences, 2020
Awareness of the logic and context of original (and subsequent) design priorities is critical to informing decisions relating to valorisation, repair, refurbishment, energy retrofit or re-use of built heritage.
Oriel Prizeman, Camilla Pezzica, Ahmed Taher, Mahdi Boughanmi   +3 more
doaj   +1 more source

Migration, Demography, and Minority Language Learning: A Case of Wales

Adeptus, 2022
The present article discusses the role of adult migrants to Wales in the country’s demographics and maintenance and promotion of the Welsh language. The Welsh society is an ageing society, predicted in the long run to rely on immigration as a solution ...
Karolina Rosiak
doaj   +1 more source

Cognitive Reserve in Parkinson's Disease: The Effects of Welsh-English Bilingualism on Executive Function

Parkinson's Disease, 2015
Objective. Bilingualism has been shown to benefit executive function (EF) and delay the onset of Alzheimer's disease. This study aims at examining whether a bilingual advantage applies to EF in Parkinson's disease (PD). Method.
J. Hindle, P. Martin-Forbes, Alexandra J M Bastable, Kirstie L. Pye, A. Martyr, C. Whitaker, F. Craik, E. Bialystok, E. Thomas, Virginia C. Mueller Gathercole, L. Clare   +10 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

AD|ARC (Administrative Data Agri-Research Collection): Linking Individual, Household and Farm Business Data for Sociodemographic Research on Farming Households

International Journal of Population Data Science
Objective To understand the socio-demographic characteristics and structure of farming households in Wales who receive subsidies compared to non-farming rural households.
Sian Morrison-Rees, Laura Madden, Matthew Curds, Paul Caskie, Rachael Loftus   +4 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source