Results 101 to 110 of about 95,890 (268)

Risk Factors of Sural Nerve Axonal Degeneration Using Clinically Relevant Thresholds in Context of Glucose Metabolism: The Maastricht Study

Muscle &Nerve, Volume 73, Issue 2, Page 283-291, February 2026.
ABSTRACT Introduction/Aims To study the association of risk factors with axonal degeneration, based on below‐threshold sural nerve amplitudes, as a proxy for distal symmetric polyneuropathy (DSP). In particular, to assess the differential contribution of risk factors in diabetes status subgroups.
Jurriaan J. A. Hodzelmans, Marcus L. F. Janssen, Jos P. H. Reulen, Annemarie Koster, Nicolaas C. Schaper, Werner H. Mess, Nadia A. Sutedja   +6 more
wiley   +1 more source

Rapamycin Exerts Its Geroprotective Effects in the Ageing Human Immune System by Enhancing Resilience Against DNA Damage

Aging Cell, Volume 25, Issue 2, February 2026.
Using in vitro DNA damage assays in human T cells, ex vivo profiling of aged immune subsets and a small placebo‐controlled in vivo study, authors show that low‐dose rapamycin, a potent life‐extending mTOR inhibitor, enhances resilience against DNA damage in the human immune system.
Loren Kell, Eleanor J. Jones, Nima Gharahdaghi, Daniel J. Wilkinson, Kenneth Smith, Philip J. Atherton, Anna K. Simon, Lynne S. Cox, Ghada Alsaleh   +8 more
wiley   +1 more source

NMNAT1 Activates Autophagy to Delay D‐Galactose‐Induced Aging in Cochlear Hair Cells

Aging Cell, Volume 25, Issue 2, February 2026.
The study presents mechanistic insights into cochlear hair cells aging using cellular and explant models. The assessment into NMNAT1 regulated NAD+ metabolism, autophagy, and aging in ARHL. NMNAT1 overexpression restores autophagic activity and decelerates aging in cochlear hair cells.
Yongjie Wei, Wenqing Yang, Han Wu, Mengdie Kong, Dachuan Fan, Yuhua Zhang, Nan Cheng, Jiawei Du, Lingna Guo, Yuyang Li, Ye Zhang, Qian Dai, Wei Cao, Jianming Yang, Qiaojun Fang   +14 more
wiley   +1 more source

Effects of Phytoplasma Infection on Aster Leafhopper (Macrosteles quadrilineatus) Settling Behavior and Development on Brassica napus

Entomologia Experimentalis et Applicata, Volume 174, Issue 2, Page 132-141, February 2026.
Aster yellows phytoplasma (AYp) infection alters host plant preference in aster leafhoppers (Macrosteles quadrilineatus), with infected vectors showing a significant preference for AYp‐infected canola (Brassica napus) early in the infection period. However, this preference fades as infection progresses. Despite early attraction, B.
Jeremy R. Irvine, Berenice Romero, Sean M. Prager   +2 more
wiley   +1 more source

WHO classification of skin tumours: key updates in the fifth edition

Histopathology, Volume 88, Issue 3, Page 555-568, February 2026.
This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy, Raymond Barnhill, Boris C. Bastian, Werner Kempf, David Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Jane Messina, Arnaud de la Fouchardière, Alexander J. Lazar, Thomas Brenn, Brian Rous, Andrew Field, Anthony Gill, Jennelle C. Hodge, Joseph D Khoury, Katia Leite, Shahin Sayed, Puay Hoon Tan, Rosalie Elenitsas, Eduardo Calonje, Lyn M. Duncan, Liang Zhiyong, Holger Moch, Rajendra Singh, Harshima Wijesinghe, Ian Cree, Dilani Lokuhetty   +29 more
wiley   +1 more source

The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins

Nature Communications, 2016
Werner syndrome is a progeroid disease characterised by genetic instability due to mutations to the WRN helicase/exonuclease. Here the authors define a novel Ku binding motif (KBM) and show that two such motifs facilitate the involvement of WRN in DNA ...
Gabrielle J. Grundy, Stuart L. Rulten, Raquel Arribas-Bosacoma, Kathryn Davidson, Zuzanna Kozik, Antony W. Oliver, Laurence H. Pearl, Keith W. Caldecott   +7 more
doaj   +1 more source

A rare urogenital malformation “Herlyn-Werner-Wunderlich syndrome” (Ohvira syndrome) discovered during an acute pelvic pain

, 2023
E. Harcha Kamal, Aouragh Ayoub, Bellajdel Ibtissam, Taheri Hafssa, Hanane Saadi, Mimouni Ahmed Ahmed   +5 more
openalex   +2 more sources

Werner's Syndrome [PDF]

BMJ, 1955
D J, ELLISON, D W, PUGH
openaire   +2 more sources

Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms [PDF]

, 2003
Terence Davis, Sim K. Singhrao, Fiona S. Wyllie, Michele F. Haughton, Paul Smith, Marie Wiltshire, David Wynford‐Thomas, Christopher J. Jones, Richard Faragher, David Kipling   +9 more
openalex   +1 more source

False consensus beliefs and populist attitudes

Political Psychology, Volume 47, Issue 1, February 2026.
Abstract A well‐established finding from social psychology is that people tend to hold “false consensus beliefs,” that is, they regularly overestimate how many others agree with their own opinions. However, the consequences of such beliefs for citizens' assessment of democratic legitimacy are still largely unexplored.
Nils D. Steiner, Claudia Landwehr, Philipp Harms   +2 more
wiley   +1 more source