Results 71 to 80 of about 848,443 (277)
, 2022 western blotting analysis of CD63,CD81,TSG101,calnexin,CD56,perforin and ...
openaire +1 more source
Effects of keratin filaments on ERK signaling during Fas-induced death of cervical cancer (HeLa) cells [PDF]
, 2014 Survival of cancer cells is influenced by a variety of factors, including physical elements such as keratin filaments. We know HeLa cells containing or lacking keratin 8/18 intermediate filaments (K+ and K- cells, respectively) are more sensitive to the ...
Berger, Amanda
core +1 more source
Caveolin-3 differentially orchestrates cholinergic and serotonergic constriction of murine airways [PDF]
, 2018 The mechanisms of controlling airway smooth muscle (ASM) tone are of utmost clinical importance as inappropriate constriction is a hallmark in asthma and chronic obstructive pulmonary disease.
Hollenhorst, M. I. +7 more
core +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Evaluation of the Western blotting method for the diagnosis of congenital toxoplasmosis
Jornal de Pediatria (Versão em Português), 2016 Objective: To evaluate the Western blotting method for the detection of IgG anti‐Toxoplasma gondii (T. gondii) (IgG‐WB) in the serum of children with suspected congenital toxoplasmosis.
Jaqueline Dario Capobiango +6 more
doaj +1 more source
The use of anti-ribosomal P antibodies in the diagnosis of cerebral lupus: superiority of western blotting over enzyme-linnked immunosorbent assay [PDF]
, 1998 This study investigated the use of anti-ribosomal P antibodies in the diagnosis of cerebral complications of systemic lupus erythematosus using two different methodsԸ?western blotting and enzyme-linked immunosorbent assay.
Chan, EYT +3 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Acta Scientiarum Polonorum: Hortorum Cultus, 2019 Dehydrins are proteins that play a role in the mechanism of drought tolerance. This study aimed at establishing dehydrin profile and accumulation in four local melon varieties of Iran: Mino, Dargazi, Saveii, and Semsori, as well as in a commercial ...
Alireza Motallebi-Azar +2 more
doaj +1 more source
A Mammalian Homolog of Drosophila melanogaster Transcriptional Coactivator Intersex Is a Subunit of the Mammalian Mediator Complex [PDF]
, 2003 The multiprotein Mediator complex is a coactivator required for transcriptional activation of RNA polymerase II transcribed genes by DNA binding transcription factors.
Banks, Charles A. S. +7 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source