Results 81 to 90 of about 2,802,888 (257)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Western Wind Quintet, November 2, 1979
, 2018 Recorded during a live performance at Oakland Recital Hall, Western Michigan University, Kalamazoo, Michigan, November 2, 1979, program no. 68 of the Department of Music's 1979-1980 season.Western Wind Quintet (Charles Osborne, flute ; Robert Humiston ...
Western Wind Quintet
core +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Análisis de la expresión transgénica en plantas, mediante la técnica Western Blotting
Acta Biológica Colombiana, 2006 La transformación de plantas mediante la tecnología del DNA recombinante es un proceso cuyo resultado debe evaluarse a nivel molecular aplicando técnicas de análisis de la expresión transgénica.
Leidy Andrea Ávila Sánchez +1 more
doaj
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Western Brass Quintet, May 16, 1977
, 2018 Recorded during a live performance at Oakland Recital Hall, Western Michigan University, Kalamazoo, , May 16, 1977, program no. 240 of the Department of Music's 1976-1977 season.Western Brass Quintet (Donald Bullock, Stephen Jones, trumpets ; Neill ...
Western Brass Quintet
core +2 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Western String Chamber Orchestra, November 21, 1994
, 2016 Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, November 21, 1994, 8:00 p.m., the 101st concert of the School of Music’s 1994-1995 season.Western String Chamber Orchestra, Bruce Uchimura,
Western String Chamber Orchestra
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Specific and versatile monoclonal antibodies for hantavirus research
mSphereRodent-borne hantaviruses pose a continual public health threat to humans through zoonotic transmission, with case fatality rates of up to 50% in some cases.
Autumn LaPointe +5 more
doaj +1 more source