Due to the increasing concern with the environmental safety and recyclability, natural fiber-reinforced composites have attracted more and more attention. In the present work, braking composite samples with and without wet granulation were fabricated and
Yucheng Liu +7 more
doaj +1 more source
Granulation techniques and technologies: recent progresses [PDF]
Granulation, the process of particle enlargement by agglomeration technique, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules.
Srinivasan Shanmugam
doaj +1 more source
Discrete element modelling of fluidised bed spray granulation [PDF]
A novel discrete element spray granulation model capturing the key features of fluidised bed hydrodynamics, liquid-solid contacting and agglomeration is presented.
Boerefijn, R. +3 more
core +13 more sources
Wet granulation of co-amorphous indomethacin systems [PDF]
The feasibility of co-amorphous systems to be wet granulated together with microcrystalline cellulose (MCC) was investigated. Solid state and molecular interactions were analysed for various co-amorphous drug-amino acid formulations of indomethacin with tryptophan and arginine, respectively, via XRPD, DSC and FTIR.
David Schütz +2 more
openaire +3 more sources
Rheology, granule growth and granule strength: Application to the wet granulation of lactose–MCC mixtures [PDF]
This study aims at better understanding the wet granulation process of a binary mixture composed of microcrystalline cellulose (water insoluble) and lactose (water soluble).
Chitu, Toma Mihai +2 more
core +3 more sources
Melt granulation as an alternative technique in solid dosage forms manufacture [PDF]
Conventional granulation methods are associated with significant disadvantages which have led to increased interest and investment in the development of alternative techniques.
Aleksić Ivana +4 more
doaj +1 more source
Wet granulation in laboratory scale high shear mixers: Effect of binder properties [PDF]
The effect of binder properties on torque curves, granule growth kinetics, wet mass consistency and dry granule strength has been investigated in this study.
Chitu, Toma Mihai +2 more
core +3 more sources
Texture analysis as a tool to study the kinetics of wet agglomeration processes [PDF]
In this work wet granulation experiments were carried out in a planetary mixer with the aim to develop a novel analytical tool based on surface texture analysis.
Codemo, Carlo +5 more
core +4 more sources
Wet granulation in laboratory-scale high shear mixers: Effect of chopper presence, design and impeller speed [PDF]
The effect of the main means of agitation in a high shear mixer has been investigated in this study. Granulation runs have been performed on a fine cohesive microcrystalline cellulose powder (Avicel 105, d50 = 20 μm) often used as a pharmaceutical ...
Chitu, Toma Mihai +2 more
core +3 more sources
Quantitative Assessment of Mass Flow Boundaries in Continuous Twin-screw Granulation
In pharmaceutical manufacturing, there is an increasing interest in continuous manufacturing. As an example for fast continuous processes in general of considerable complexity, this study was focussed on improving the understanding of twin-screw
Adrian Schmidt +4 more
doaj +1 more source

