Results 41 to 50 of about 24,687 (267)

Real-time assessment of critical quality attributes of a continuous granulation process [PDF]

, 2013
There exists the intention to shift pharmaceutical manufacturing of solid dosage forms from traditional batch production towards continuous production. The currently applied conventional quality control systems, based on sampling and time-consuming off ...
Córdoba Díaz, Damián, De Beer, Thomas, Fonteyne, Margot, Gildemyn, Delphine, Remon, Jean Paul, Vercruysse, Jurgen, Vervaet, Chris   +6 more
core   +1 more source

Wet granulation: the effect of shear on granule properties [PDF]

Powder Technology, 2003
This paper presents a study of the wet granulation of fine cosmetic particles using a high-shear mixer granulator on a given particle and binder system. The shear effect on granule properties is highlighted. The granules formed under different impeller speeds are divided into size classes and further examined in terms of porosity, friability and binder
D Oulahna, F Cordier, L Galet, J.A Dodds
openaire   +1 more source

Wet granulation multiscale modelling accelerated via CG-DEM [PDF]

EPJ Web of Conferences
Wet agglomeration is a complex particulate process driven by multiple microscale mechanisms. Discrete Element Modeling (DEM) enables a deeper understanding of these mechanisms and supports process optimization.
Saghafian Larijani Roxana, Luding Stefan, Magnanimo Vanessa   +2 more
doaj   +1 more source

Four‐Point Bending Tests at High Temperatures on Commercial MgO‐C Refractory Bricks with and Without Recyclate Considering Different Carbon Contents

Advanced Engineering Materials, EarlyView.
Four‐point bending tests are conducted in an argon atmosphere on commercial MgO‐C brick grades with and without MgO‐C recyclate from room temperature up to 1300 °C. No detrimental effect of the MgO‐C recyclates on bending strength is found. Instead, a decisive influence of the total carbon content is observed, with lower total carbon contents ...
Alexander Schramm, Lukas Knöchel, Thomas Schemmel, Christos G. Aneziris, Anja Weidner, Horst Biermann   +5 more
wiley   +1 more source

Volume fraction variations and dilation in colloids and granulars [PDF]

, 2009
Discusses the importance of spatial and temporal variations in particle volume fraction to understanding the force response of concentrated colloidal suspensions and granular ...
Cates M. E., Metzner A. B.
core   +1 more source

Enhancing dissolution of artesunate from immediate release tablets using a green granulation technique

Archives of Pharmaceutical Sciences Ain Shams University, 2019
Artesunate is a poorly soluble drug and liable to aqueous hydrolysis. This study aims to formulate Artesunate as an immediate release tablet through optimization of the melt granulation technique to improve the dissolution of the drug.
Akram ahmad Bashir , sameh abd-elhamid, Alia Badawi, Ahmed S. Geneidi   +3 more
doaj   +1 more source

Characterization of a Recyclate‐Based MgO‐Steel Composite As‐Sintered Inert Anode Candidate After Exposure to Cryolite Electrolysis

Advanced Engineering Materials, EarlyView.
Carbon‐free inert anodes are essential for decarbonizing aluminum electrolysis. This study investigates a recyclate‐based MgO‐316L steel composite anode tested under galvanostatic Hall–Héroult conditions in cryolite at 1000°C. Microstructural analysis reveals selective MgO fluorination, spinel and oxide layer formation, electrolyte infiltration, and ...
Serhii Yaroshevskyi, Alexander Adamczyk, Nora Brachhold, Gert Schmidt, Jana Hubálková, R. Gumeniuk, Alexandros Charitos, Christos G. Aneziris   +7 more
wiley   +1 more source

Enhancing the Poor Flow and Tableting Problems of High Drug-Loading Formulation of Canagliflozin Using Continuous Green Granulation Process and Design-of-Experiment Approach

Pharmaceuticals, 2020
Maximization of drug-loading can significantly reduce the size of dosage form and consequently decrease the cost of manufacture. In this research, two challenges were addressed: poor flow and tableting problems of high-drug loading (>70%) formulation of ...
Bjad K. Almutairy, El-Sayed Khafagy, Ahmed Alalaiwe, Mohammed F. Aldawsari, Saad M. Alshahrani, Bader B. Alsulays, Abdullah S. Alshetaili, Sultan M. Alshehri, Mohamed H. Fayed   +8 more
doaj   +1 more source

Rapid Sintering of Porous Organic Polymer Powders Into Mechanically Strong Monoliths for Efficient CO2 Capture

Advanced Functional Materials, EarlyView.
Spark plasma sintering enables rapid processing of porous organic polymer (POP) from fine powders to a freestanding and mechanically robust monolith. The sintering process retains the CO2 adsorption capacity and CO2/N2 selectivity, making the monolith more suitable as a solid sorbent for practical carbon capture applications.
Duan Li, Tianhui Shi, Sirui Ran, Lei Zeng, Chao Xu   +4 more
wiley   +1 more source

Ibuprofen-loaded calcium phosphate granules : combination of innovative characterization methods to relate mechanical strength to drug location [PDF]

, 2010
This paper studies the impact of the location of a drug substance on the physicochemical and mechanical properties of two types of calcium phosphate granules loaded with seven different contents of ibuprofen, ranging from 1.75% to 46%.
Ahola, Ayers, Bohner, Brunauer, Charnay, Chevalier, Chevalier, Corry, Costa, D. Chulia, Daculsi, Daculsi, De Peinder, Dubois, E. Chevalier, Fernandez-Carballido, Gabaude, Ginebra, Hasegawa, Hiestand, Huber, Hulbert, J. Dubois, L. Makein, Ladrón de Guevara-Fernández, Lawn, LeGeros, Li, M. Viana, Marchi, Melville, Mendez, Otsuka, Passuti, Pitchumani, Quinn, Ruotsalainen, Räsänen, S. Cazalbou, Sivakumar, Uchida, Vallet-Regí, Viana, Yang, Zeitler   +44 more
core   +3 more sources