Results 191 to 200 of about 57,794 (383)

Analysis of lncRNA–mRNA networks after MEK1/2 inhibition based on WGCNA in pancreatic ductal adenocarcinoma [PDF]

open access: hybrid, 2019
Jing Qian   +11 more
openalex   +1 more source

Below‐ground drivers of rhizosphere functional gene assembly during Moso bamboo expansion

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Moso bamboo (Phyllostachys edulis) expansion threatens subtropical forest biodiversity, yet how intraspecific root trait variation shapes rhizosphere microbial functional potential remains unclear.
Yaoxing Wu   +8 more
wiley   +1 more source

Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis. [PDF]

open access: yes, 2019
The development of the mammalian retina is a complicated process involving the generation of distinct types of neurons from retinal progenitor cells (RPCs) in a spatiotemporal-specific manner.
An, Qin   +9 more
core  

Additional file 10 of Single-cell and WGCNA uncover a prognostic model and potential oncogenes in colorectal cancer

open access: green, 2022
Ziyang Di   +8 more
openalex   +1 more source

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

open access: yesAllergy, EarlyView.
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong   +217 more
wiley   +1 more source

Mediation of Polygenic Asthma Risk Through Gene Expression

open access: yesAllergy, EarlyView.
We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan   +29 more
wiley   +1 more source

Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses

open access: yesAllergy, EarlyView.
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong   +5 more
wiley   +1 more source

Identification of Novel Gene Signature Predicting Lymph Node Metastasis in Papillary Thyroid Cancer via Bioinformatics Analysis and in vitro Validation

open access: yesInternational Journal of General Medicine
Hai Li,1,2 Dongnan Sun,3 Kai Jin,4 Xudong Wang1 1Department of Maxillofacial and Otorhinolaryngological Oncology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Basic and Translational Medicine on Head & Neck Cancer, Key ...
Li H, Sun D, Jin K, Wang X
doaj  

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