Network Analysis Identifies Microsomal Glutathione S-Transferase as a Potential Regulator of Oxidative Stress and Proteasome Dysfunction in Human Osteoarthritic Menisci. [PDF]
Wu X +7 more
europepmc +1 more source
Integrative Transcriptome Analysis and WGCNA Uncover the Growth Regulatory Mechanisms in <i>Cephalopholis sonnerati</i>. [PDF]
Wang Z +5 more
europepmc +1 more source
TRIP13 identified by WGCNA as a progression-related and prognostic biomarker in ovarian cancer. [PDF]
Zhang H, Zhang M, Hu Y, He Y.
europepmc +1 more source
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Application of WGCNA and PloGO2 in the Analysis of Complex Proteomic Data
2021In this protocol we describe our workflow for analyzing complex, multi-condition quantitative proteomic experiments, with the aim to extract biological insights. The tool we use is an R package, PloGO2, contributed to Bioconductor, which we can optionally precede by running correlation network analysis with WGCNA.
Wu, Jemma X. +4 more
openaire +3 more sources
Identification of key pathways and genes in the progression of silicosis based on WGCNA
Inhalation Toxicology, 2022Silicosis, induced by inhaling silica particles in workplaces, is one of the most common occupational diseases. The prognosis of silicosis and its consequent fibrosis is extremely poor due to limited treatment modalities and lack of understanding of the disease mechanisms.
Jiaqi Lv +18 more
openaire +2 more sources
WGCNA Application to Proteomic and Metabolomic Data Analysis
2017Progresses in mass spectrometric instrumentation and bioinformatics identification algorithms made over the past decades allow quantitative measurements of relative or absolute protein/metabolite amounts in cells in a high-throughput manner, which has significantly expedited the exploration into functions and dynamics of complex biological systems ...
G, Pei, L, Chen, W, Zhang
openaire +2 more sources
Identifying novel candidate biomarkers of RCC based on WGCNA analysis
Personalized Medicine, 2018Extracting differential expression genes (DEGs) is an effective approach to improve the accuracy of determining the candidate biomarker genes. However, the previous DEGs analysis methods ignore that the expression levels of genes in different pathology stages of cancers are complex and various.In our study, staging DEGs analysis and weighted gene co ...
Jin, Deng +4 more
openaire +2 more sources
[WGCNA screening of prognostic markers in medulloblastoma].
Zhonghua yi xue za zhi, 2020Objective: In this study, we used the Weighted gene co-expression network analysis (WGCNA) analysis to find the gene module that are specifically expressed in Medulloblastoma and screened the marker genes that may diagnose and treat Medulloblastoma. Methods: WGCNA was used to identify the gene modules that are specifically associated with suvival in ...
B S, Du, L, Yuan, L G, Sun, Z Y, Zhang
openaire +1 more source

