Results 31 to 40 of about 5,237 (144)

Culturing on Wharton's jelly extract delays mesenchymal stem cell senescence through p53 and p16INK4a/pRb pathways. [PDF]

PLoS ONE, 2013
Mesenchymal stem cells (MSCs) hold great therapeutic potential. However, MSCs undergo replication senescence during the in vitro expansion process. Wharton's jelly from the human umbilical cord harbors a large number of MSCs.
Haojie Hao, Guanghui Chen, Jiejie Liu, Dongdong Ti, Yali Zhao, Shenjun Xu, Xiaobing Fu, Weidong Han   +7 more
doaj   +1 more source

Additional file 1: Table S1. of Epigenetic reprogramming converts human Whartonâ s jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators

, 2017
Presenting cardiac-specific gene primers, Table S2 presenting Wnt-related gene primers, Table S3 presenting stemness and noncardiac gene primers, and Table S4 presenting methylation-specific primers. (DOCX 20 kb)
Bhuvanalakshmi, G., Arfuso, Frank, Kumar, Alan, Dharmarajan, Arun, Warrier, Sudha   +4 more
openaire   +1 more source

Additional file 2: of Xenografting of human umbilical mesenchymal stem cells from Whartonâ s jelly ameliorates mouse spinocerebellar ataxia type 1

, 2019
Figure S2. Quantitative method of Purkinje cell number in the Lobules III and VI. The cerebellar slices of all groups were immunostained with anti-calbindin to label the Purkinje cell. Quantitative analysis of Purkinje cell number was made according to numbers of Purkinje cell (red) in the unit length of Purkinje cell layer (green line) in Lobules III ...
Tsai, Pei-Jiun, Yeh, Chang-Ching, Huang, Wan-Jhen, Min, Ming-Yuan, Huang, Tzu-Hao, Ko, Tsui-Ling, Huang, Pei-Yu, Chen, Tien-Hua, Hsu, Sanford, Soong, Bing-Wen, Fu, Yu-Show   +10 more
openaire   +1 more source

Pengaruh Pemberian Mesenchymal Stem Cell Wharton Jelly terhadap Ekspresi Gen Glut-4 Pada Tikus Alzheimer

Majalah Kedokteran Andalas, 2023
Tujuan: Melihat ekspresi gen Glut-4 pada otak tikus yang mengalami Alzheimer dengan induksi AlCl3, setelah diberikan Mesechymal Stem Cells-Wharton’s Jelly (MSC-WJ).
Berlianisa Berlianisa
doaj   +1 more source

Characterization of the extracellular matrix from human and dog umbilical cords

The Anatomical Record, EarlyView.
Abstract The extracellular matrix is important for maintaining tissue morphogenesis and homeostasis; it can also be used as a biomaterial for the production of biological scaffolds. Particularly, the umbilical cord has shown potential in the production of scaffolds for small‐diameter vessels.
Ana Carla Mendonça, Roberta Losi Guembarovski, Carlos Alberto Miqueloto, Alda Fiorina Maria Losi Guembarovski, Caio Garcia Barbosa da Silva, Laís Capelasso Lucas Pinheiro, Phelipe Oliveira Favaron   +6 more
wiley   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Expression of early transcription factors by mesenchymal stem cells derived from ovine umbilical cord Wharton’s jelly

Indian Journal of Animal Sciences, 2016
Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into mesodermal lineages. Despite major progress in our general knowledge related to the application of adult stem cells, finding alternative sources for bone marrow MSCs ...
S ESWARI, M MONISHA, K VIJAYARANI, K KUMANAN   +3 more
doaj   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Migration of Human Wharton’s Jelly Stem Cells Seeded Onto the Chorioallantoic Membrane Into the Chick Liver [PDF]

Journal of Kerman University of Medical Sciences
Background: Developing chicken embryo culture techniques provides methods for manipulating chicken embryos. In this study, the cell-based approach investigated human Wharton›s jelly stem cells (HWJSCs) proliferation and migration into internal embryonic ...
Amin Derakhshanfar, Javad Moayedi, Seyedeh-Sara Hashemi, Iman Jamhiri, Zeinab Dehghan   +4 more
doaj   +1 more source

Human umbilical cord Wharton's jelly-derived mesenchymal stem cell transplantation could improve diabetic intracavernosal pressure

Asian Journal of Andrology, 2022
Mesenchymal stem cells (MSCs) secrete various cytokines with angiogenic and neuroprotective effects. This study aimed to assess the effects of human umbilical cord Wharton's jelly-derived MSCs (hWJ-MSCs) on diabetes-related intracavernosal pressure (ICP)
Jian-Hong Wu, Dong-Ya Wang, Lu Sheng, Wei-Qing Qian, Shu-Jie Xia, Qi Jiang   +5 more
doaj   +1 more source