Results 31 to 40 of about 5,219 (144)

Additional file 3: of Xenografting of human umbilical mesenchymal stem cells from Whartonâ s jelly ameliorates mouse spinocerebellar ataxia type 1

open access: yes, 2019
Figure S3. Low-magnification images show the anti-calbindin immunostaining for Purkinje cells in cerebellum. The cerebellar slices of all groups were immunostained with anti-calbindin to label Purkinje cells in cerebellum (Column A for Normal group, B for Normal-PBS group, C for SCA1 group, D for SCA1-PBS group, and E for SAC1-HUMSCs group).
Pei-Jiun Tsai   +10 more
openaire   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

open access: yesAdvanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim   +2 more
wiley   +1 more source

Additional file 4: of Xenografting of human umbilical mesenchymal stem cells from Whartonâ s jelly ameliorates mouse spinocerebellar ataxia type 1

open access: yes, 2019
Figure S4. Human cytokine antibody array of the mouse cerebella. One hundred and seventy-four human cytokines were blotted onto the membranes and their corresponding positions are shown as in the right panels. Five growth-promoting human cytokines were significantly increased in the SCA1-HUMSCs group. (PDF 179 kb)
Tsai, Pei-Jiun   +10 more
openaire   +1 more source

Characterization of the extracellular matrix from human and dog umbilical cords

open access: yesThe Anatomical Record, EarlyView.
Abstract The extracellular matrix is important for maintaining tissue morphogenesis and homeostasis; it can also be used as a biomaterial for the production of biological scaffolds. Particularly, the umbilical cord has shown potential in the production of scaffolds for small‐diameter vessels.
Ana Carla Mendonça   +6 more
wiley   +1 more source

Expression of early transcription factors by mesenchymal stem cells derived from ovine umbilical cord Wharton’s jelly

open access: yesIndian Journal of Animal Sciences, 2016
Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into mesodermal lineages. Despite major progress in our general knowledge related to the application of adult stem cells, finding alternative sources for bone marrow MSCs ...
S ESWARI   +3 more
doaj   +1 more source

Human umbilical cord Wharton's jelly-derived mesenchymal stem cell transplantation could improve diabetic intracavernosal pressure

open access: yesAsian Journal of Andrology, 2022
Mesenchymal stem cells (MSCs) secrete various cytokines with angiogenic and neuroprotective effects. This study aimed to assess the effects of human umbilical cord Wharton's jelly-derived MSCs (hWJ-MSCs) on diabetes-related intracavernosal pressure (ICP)
Jian-Hong Wu   +5 more
doaj   +1 more source

Additional file 1: Table S1. of Epigenetic reprogramming converts human Whartonâ s jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators

open access: yes, 2017
Presenting cardiac-specific gene primers, Table S2 presenting Wnt-related gene primers, Table S3 presenting stemness and noncardiac gene primers, and Table S4 presenting methylation-specific primers. (DOCX 20 kb)
Bhuvanalakshmi, G.   +4 more
openaire   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

open access: yesBMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu   +9 more
wiley   +1 more source

Additional file 2: of Xenografting of human umbilical mesenchymal stem cells from Whartonâ s jelly ameliorates mouse spinocerebellar ataxia type 1

open access: yes, 2019
Figure S2. Quantitative method of Purkinje cell number in the Lobules III and VI. The cerebellar slices of all groups were immunostained with anti-calbindin to label the Purkinje cell. Quantitative analysis of Purkinje cell number was made according to numbers of Purkinje cell (red) in the unit length of Purkinje cell layer (green line) in Lobules III ...
Tsai, Pei-Jiun   +10 more
openaire   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro   +5 more
wiley   +1 more source

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