Results 51 to 60 of about 5,219 (144)

Surface N‐Glycosylation Dictates MSC‐EV Uptake and CCR2‐Driven Monocyte Recruitment to Inflamed Endothelium Under Shear Flow

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Mesenchymal stromal cell‐derived extracellular vesicles (MSC‐EV) hold promising potential for immunomodulation and tissue regeneration, especially for treating ischemia‐reperfusion injury (IRI). However, their therapeutic use is hindered by challenges in tissue targeting and incomplete understanding of their functional mechanisms.
Marta Clos‐Sansalvador, Marta Monguió‐Tortajada, Sergio G. Garcia, Manuel Pérez‐Martínez, Marta Sanroque‐Muñoz, Miriam Font‐Morón, Diego Megías, Isabel Peset, Marcella Franquesa, Marta Hergueta‐Redondo, Hector Peinado, Francesc E. Borràs   +11 more
wiley   +1 more source

Semi‐Automated Platform for Early Prenatal Coelocentesis Testing Using Electrospun Nanofiber Technology

Macromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.
A semi‐automated approach for early prenatal diagnosis is developed for low‐cellularity samples from coelocentesis by exploiting biotin/streptavidin interaction to functionalize electrospun mats with antibodies. With potential microfluidic integration, the resulting platform enables fetal cell capture, offering a strategy toward improved efficiency and
Emanuela Muscolino, Anna Barbara Di Stefano, Santina Acuto, Clelia Dispenza   +3 more
wiley   +1 more source

Wharton’s jelly absence: a possible cause of stillbirth

Autopsy and Case Reports, 2013
The umbilical cord is a structure that provides vascular flow between the fetus and the placenta. It contains two arteries and one vein, which are surrounded and supported by gelatinous tissue known as Wharton’s jelly.
Eduarda Bittencourt Damasceno, Patrícia Picciarelli de Lima   +1 more
doaj  

Management of retinitis pigmentosa by Wharton’s jelly derived mesenchymal stem cells: preliminary clinical results

Stem Cell Research & Therapy, 2020
Purpose The aim of this study is to determine if umbilical cord Wharton’s jelly derived mesenchymal stem cells implanted in sub-tenon space have beneficial effects on visual functions in retinitis pigmentosa patients by reactivating the degenerated ...
Emin ÖZMERT, Umut ARSLAN
doaj   +1 more source

Hybrid Multiphoton Lithography Scaffolds for Nanoscale Mechanobiological Assessment in Microscale Bone Models

Small, Volume 22, Issue 33, 12 June 2026.
This work presents a 3D hybrid tissue scaffold inspired by bone, incorporating collagen, fabricated using multiphoton lithography. The mechanical properties of collagen are tunable, and biodegradation allows for time‐dependent changes in geometry. The results demonstrate enhanced osteogenic differentiation of stem cells in our hybrid scaffolds.
Christoph Naderer, Eleni Priglinger, Martina Ramsauer, Cornelia Bergmayr, Tobias Gotterbarm, Sofia Danilchenko, Dmitry Sivun, Jaroslaw Jacak   +7 more
wiley   +1 more source

Development of Human Umbilical Vessels in The Second Trimester of Pregnancy: Histological, Immunohistochemical and Morphometric Study [PDF]

The Egyptian Journal of Histology, 2017
Introduction: There are many publications describing structure of full term umbilical vessels, however, few studies in early gestation.Aim: To elucidate changes in microstructure of developing umbilical vessels in the second trimester of pregnancy ...
Nagwa EI-Nefiawy
doaj   +1 more source

Assessing the Outcomes and Complications of Skin Allografts in Healing Diabetic Foot and Venous Leg Ulcers: A Systematic Review of Randomised Controlled Trials

International Wound Journal, Volume 23, Issue 6, June 2026.
ABSTRACT Chronic diabetic foot ulcers and venous leg ulcers remain difficult to treat due to delayed healing and high complication rates. Biologic skin allografts derived from living or amniotic tissue provide extracellular matrix components, cytokines, growth factors and viable cells that facilitate tissue repair.
Christopher Mathe, Sachin Reddi, William Nahm, Aryaman Trikala, Samuel Schwartz   +4 more
wiley   +1 more source

Histomorphology of Pancreatic Islet in Physiological Aging Female Rats Post Intravenous Human Wharton's Jelly Mesenchymal Stem Cell Injection

Journal of Stem Cell Research and Tissue Engineering, 2019
The increasing population of aged people will have the important role in the life, but the function of their bodies will decrease because of aging. Aging will increase the risk of degenerative disease, one of example is diabetes.
wining astini
doaj   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Prevention of stillbirths associated with umbilical cord abnormalities: A clinico‐pathological overview

International Journal of Gynecology &Obstetrics, Volume 173, Issue 2, Page 635-653, May 2026.
Abstract Stillbirths affect millions of pregnancies every year worldwide, and obstruction of the umbilical cord blood flow is one of the main causes of fetal death. This review provides a clinico‐pathological overview of cord abnormalities potentially associated with antepartum stillbirth, describing the mechanism determining the death and addressing ...
Laura Avagliano, Chiara Parodi, Valentina Massa, Gaetano Bulfamante   +3 more
wiley   +1 more source