Results 51 to 60 of about 5,237 (144)

Umbilical cord Wharton's jelly repeated culture system: a new device and method for obtaining abundant mesenchymal stem cells for bone tissue engineering. [PDF]

PLoS ONE, 2014
To date, various types of cells for seeding regenerative scaffolds have been used for bone tissue engineering. Among seed cells, the mesenchymal stem cells derived from human umbilical cord Wharton's jelly (hUCMSCs) represent a promising candidate and ...
Zhengqi Chang, Tianyong Hou, Junchao Xing, Xuehui Wu, Huiyong Jin, Zhiqiang Li, Moyuan Deng, Zhao Xie, Jianzhong Xu   +8 more
doaj   +1 more source

Efficacy and Safety of Intracoronary Mesenchymal Stem Cell Administration in ST‐Segment Elevation Acute Myocardial Infarction: A Meta‐Analysis of Randomized Controlled Trials

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT ST‐segment elevation myocardial infarction (STEMI) remains a major cause of cardiovascular mortality and morbidity worldwide. Despite advances in reperfusion therapy, many patients still develop irreversible myocardial injury and adverse ventricular remodeling. Intracoronary mesenchymal stem cell (MSC) administration has been investigated as a
Kaiming Chen, Shijie Zhao, Xiaoqian Zou, Zhaoshuang Zhong, Shuyue Xia   +4 more
wiley   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, Volume 13, Issue 40, 17 July 2026.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Integrating Nuclear Magnetic Resonance into Bioprocess Control of Clinical‐Grade Extracellular Vesicle Manufacturing

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
Nuclear magnetic resonance (NMR) in bioprocess design for the production of extracellular vesicles (EVs). NMR‐metabolomics enables real‐time bioprocess intelligence, bridging biological complexity with GMP rigor and accelerating the clinical translation of EV‐based therapies.
Santiago Roura, Núria Amigó, Joaquim Vives   +2 more
wiley   +1 more source

Wharton’s jelly absence: a possible cause of stillbirth

Autopsy and Case Reports, 2013
The umbilical cord is a structure that provides vascular flow between the fetus and the placenta. It contains two arteries and one vein, which are surrounded and supported by gelatinous tissue known as Wharton’s jelly.
Eduarda Bittencourt Damasceno, Patrícia Picciarelli de Lima   +1 more
doaj  

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

Management of retinitis pigmentosa by Wharton’s jelly derived mesenchymal stem cells: preliminary clinical results

Stem Cell Research & Therapy, 2020
Purpose The aim of this study is to determine if umbilical cord Wharton’s jelly derived mesenchymal stem cells implanted in sub-tenon space have beneficial effects on visual functions in retinitis pigmentosa patients by reactivating the degenerated ...
Emin ÖZMERT, Umut ARSLAN
doaj   +1 more source

Engineering Functional Graphenic Materials for Bone Repair

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 4, July/August 2026.
Graphene oxide (GO) and its derivatives have many favorable properties for biomedical applications. This is due to the inherent properties of GO including high surface area, functionalizability, mechanical strength, and bioresorbable nature, among other properties outlined above.
Sebastian Guajardo, Jason D. Orlando, Chenyun Deng, Anne M. Arnold, Stefanie A. Sydlik   +4 more
wiley   +1 more source

Development of Human Umbilical Vessels in The Second Trimester of Pregnancy: Histological, Immunohistochemical and Morphometric Study [PDF]

The Egyptian Journal of Histology, 2017
Introduction: There are many publications describing structure of full term umbilical vessels, however, few studies in early gestation.Aim: To elucidate changes in microstructure of developing umbilical vessels in the second trimester of pregnancy ...
Nagwa EI-Nefiawy
doaj   +1 more source

Mesenchymal Stem Cell‐Derived Exosomes Improve Aging‐Related Changes in Liver Lipid Metabolism by Enhancing Autophagy

Aging Cell, Volume 25, Issue 7, July 2026.
Schematic summary of the protective effects of HucMSC‐derived exosomes (HucMDEs) against aging‐related hepatic lipid metabolism disorders through autophagy enhancement. ABSTRACT Health problems associated with aging have become increasingly severe in recent years.
Jinquan Li, Mengqi Gao, Jinke Feng, Dini Huo, Rui Hong, Fuhua Zhang, Qin He, Ming Dong   +7 more
wiley   +1 more source