Results 61 to 70 of about 5,237 (144)

Histomorphology of Pancreatic Islet in Physiological Aging Female Rats Post Intravenous Human Wharton's Jelly Mesenchymal Stem Cell Injection

Journal of Stem Cell Research and Tissue Engineering, 2019
The increasing population of aged people will have the important role in the life, but the function of their bodies will decrease because of aging. Aging will increase the risk of degenerative disease, one of example is diabetes.
wining astini
doaj   +1 more source

Surface N‐Glycosylation Dictates MSC‐EV Uptake and CCR2‐Driven Monocyte Recruitment to Inflamed Endothelium Under Shear Flow

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Mesenchymal stromal cell‐derived extracellular vesicles (MSC‐EV) hold promising potential for immunomodulation and tissue regeneration, especially for treating ischemia‐reperfusion injury (IRI). However, their therapeutic use is hindered by challenges in tissue targeting and incomplete understanding of their functional mechanisms.
Marta Clos‐Sansalvador, Marta Monguió‐Tortajada, Sergio G. Garcia, Manuel Pérez‐Martínez, Marta Sanroque‐Muñoz, Miriam Font‐Morón, Diego Megías, Isabel Peset, Marcella Franquesa, Marta Hergueta‐Redondo, Hector Peinado, Francesc E. Borràs   +11 more
wiley   +1 more source

Wharton's jelly stem cells delivered via a curcumin-loaded nanofibrous wound dressings improved diabetic wound healing via upregulating VEGF and IGF genes: An in vitro and in vivo study

Regenerative Therapy
Diabetic wounds pose an enduring clinical hurdle, marked by delayed recovery, persistent inflammation, and an elevated susceptibility to infections.
Chengjin Chen, Hui Zhao, Wenlu Zhang, Xuelan Hong, Shengjie Li, Saeed Rohani   +5 more
doaj   +1 more source

Novel Sources of Fetal Stem Cells for Future Regenerative Medicine

Indonesian Biomedical Journal, 2012
BACKGROUND: Mesenchymal stromal cells are multipotent cells considered to be of great promise for use in regenerative medicine. However, the cell dose may be a critical factor in many clinical conditions and the yield resulting from the ex vivo expansion
Yani Lina, Andi Wijaya
doaj   +1 more source

Semi‐Automated Platform for Early Prenatal Coelocentesis Testing Using Electrospun Nanofiber Technology

Macromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.
A semi‐automated approach for early prenatal diagnosis is developed for low‐cellularity samples from coelocentesis by exploiting biotin/streptavidin interaction to functionalize electrospun mats with antibodies. With potential microfluidic integration, the resulting platform enables fetal cell capture, offering a strategy toward improved efficiency and
Emanuela Muscolino, Anna Barbara Di Stefano, Santina Acuto, Clelia Dispenza   +3 more
wiley   +1 more source

Hybrid Multiphoton Lithography Scaffolds for Nanoscale Mechanobiological Assessment in Microscale Bone Models

Small, Volume 22, Issue 33, 12 June 2026.
This work presents a 3D hybrid tissue scaffold inspired by bone, incorporating collagen, fabricated using multiphoton lithography. The mechanical properties of collagen are tunable, and biodegradation allows for time‐dependent changes in geometry. The results demonstrate enhanced osteogenic differentiation of stem cells in our hybrid scaffolds.
Christoph Naderer, Eleni Priglinger, Martina Ramsauer, Cornelia Bergmayr, Tobias Gotterbarm, Sofia Danilchenko, Dmitry Sivun, Jaroslaw Jacak   +7 more
wiley   +1 more source

Wharton’s Jelly Tissue Allograft for Connective Tissue Defects Surrounding Nerves in the Tarsal Tunnel: A Retrospective Case Series

Reports
Caused by age or trauma, collapsed connective tissue can cause nerve entrapment and damage within the tarsal tunnel. Tarsal tunnel syndrome is relatively underdiagnosed. This study presents an intervention targeting damaged tissues surrounding the nerves
Ronald Bruton, Tracie L. Gilliland, John J. Shou, Crislyn G. Woods, Naomi E. Lambert, Tyler C. Barrett   +5 more
doaj   +1 more source

Metabolic Remodeling during Neuronal Induction of Human Wharton’s Jelly Mesenchymal Stem Cells: From Glycolysis to Oxidative Pathways

Neurological Sciences and Neurophysiology
Background: Stem cells, known for their self-renewal and differentiation capabilities, exhibit unique metabolic characteristics that play a crucial role in cellular differentiation.
Irem Nur Gökbayrak Atay, Ramazan Uğur Bora, Mine Arayici, Nevin Deniz Kirca, Tuğba San Erkoç, Pinar Akan   +5 more
doaj   +1 more source

Therapeutic Effects of Wharton’s Jelly Mesenchymal Stem Cells: from Laboratory to Clinical Application [PDF]

Brazilian Archives of Biology and Technology
Stem cells are a promising solution for repaired damage tissue. Isolation of this cell from tissue, proliferation in vitro, and implanting them in damaged tissue microenvironment are the basic strategy of Regenerative medicine.
Nastaran Azarbarz, Fatemeh Rezaei-Tazangi, Zeinab Shafiei Seifabadi, Darioush Bijan Nejad   +3 more
doaj   +1 more source

Quercetin-loaded mesenchymal stem cell derived extracellular vesicles enhance ovarian function in a cyclophosphamide induced ovarian damage

Journal of Ovarian Research
Background To investigate whether intraovarian administration of quercetin-loaded extracellular vesicles derived from Wharton’s jelly mesenchymal stem cells (EVs-QUE) improves ovarian function in a cyclophosphamide (CTX)-induced premature ovarian ...
Zeynep Ece Utkan Korun, Zehra Seda Halbutogullari, Yusufhan Yazir, Selenay Furat, Candan Altuntas, Ahmet Ozturk, Tugba Koldankaya, Serap Mert, Erkut Attar   +8 more
doaj   +1 more source