Results 61 to 70 of about 5,219 (144)

Wharton's jelly stem cells delivered via a curcumin-loaded nanofibrous wound dressings improved diabetic wound healing via upregulating VEGF and IGF genes: An in vitro and in vivo study

Regenerative Therapy
Diabetic wounds pose an enduring clinical hurdle, marked by delayed recovery, persistent inflammation, and an elevated susceptibility to infections.
Chengjin Chen, Hui Zhao, Wenlu Zhang, Xuelan Hong, Shengjie Li, Saeed Rohani   +5 more
doaj   +1 more source

Novel Sources of Fetal Stem Cells for Future Regenerative Medicine

Indonesian Biomedical Journal, 2012
BACKGROUND: Mesenchymal stromal cells are multipotent cells considered to be of great promise for use in regenerative medicine. However, the cell dose may be a critical factor in many clinical conditions and the yield resulting from the ex vivo expansion
Yani Lina, Andi Wijaya
doaj   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, Volume 4, Issue 3, May 2026.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Adipose‐derived and bone marrow aspirate concentrate injections for osteoarthritis: A scoping review

PM&R, Volume 18, Issue S2, Page S6-S19, May 2026.
Abstract Background Osteoarthritis is a leading cause of disability worldwide, and cell‐based treatments including adipose‐derived and bone marrow aspirate have been sought by the lay and medical community as treatment options. Objective To perform a scoping review of published literature on cell‐based injections allowed by the U.S.
Leonardo P. Oliveira, Aaron Lear, Joseph Elphingstone, Derek Stokes, Rachel Chamberlain, Timothy Tiu, David Price, Megan Agnew, Stephanie Kliethermes, Sarah Sund, Leslie A. Christensen, Shane Shapiro, Kenneth Mautner   +12 more
wiley   +1 more source

Intrapartum CTG characteristics associated with isolated single umbilical artery in term fetuses: A matched case–control study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 5, Page 930-939, May 2026.
Fetuses with isolated single umbilical artery (iSUA) were shown to exhibit a higher percentage of late decelerations and shorter decelerations. Fetuses with iSUA show a higher prevalence of overshoots and longer fetal heart reate (FHR) recovery duration.
Phebe B. Q. Berben, Ivar R. de Vries, Rik Vullings, M. Beatrijs van der Hout‐van der Jagt, S. Guid Oei, Judith O. E. H. van Laar   +5 more
wiley   +1 more source

BKCa channels regulate the immunomodulatory properties of WJ-MSCs by affecting the exosome protein profiles during the inflammatory response

Stem Cell Research & Therapy, 2020
Background Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) from the human umbilical cord have been studied extensively due to their immunomodulatory functions.
Ahui Song, Jingjing Wang, Yan Tong, Junyan Fang, Yi Zhang, Huiping Zhang, Hongqiang Ruan, Kai Wang, Yingli Liu   +8 more
doaj   +1 more source

Wharton’s Jelly Tissue Allograft for Connective Tissue Defects Surrounding Nerves in the Tarsal Tunnel: A Retrospective Case Series

Reports
Caused by age or trauma, collapsed connective tissue can cause nerve entrapment and damage within the tarsal tunnel. Tarsal tunnel syndrome is relatively underdiagnosed. This study presents an intervention targeting damaged tissues surrounding the nerves
Ronald Bruton, Tracie L. Gilliland, John J. Shou, Crislyn G. Woods, Naomi E. Lambert, Tyler C. Barrett   +5 more
doaj   +1 more source

Metabolic Remodeling during Neuronal Induction of Human Wharton’s Jelly Mesenchymal Stem Cells: From Glycolysis to Oxidative Pathways

Neurological Sciences and Neurophysiology
Background: Stem cells, known for their self-renewal and differentiation capabilities, exhibit unique metabolic characteristics that play a crucial role in cellular differentiation.
Irem Nur Gökbayrak Atay, Ramazan Uğur Bora, Mine Arayici, Nevin Deniz Kirca, Tuğba San Erkoç, Pinar Akan   +5 more
doaj   +1 more source

Therapeutic Effects of Wharton’s Jelly Mesenchymal Stem Cells: from Laboratory to Clinical Application [PDF]

Brazilian Archives of Biology and Technology
Stem cells are a promising solution for repaired damage tissue. Isolation of this cell from tissue, proliferation in vitro, and implanting them in damaged tissue microenvironment are the basic strategy of Regenerative medicine.
Nastaran Azarbarz, Fatemeh Rezaei-Tazangi, Zeinab Shafiei Seifabadi, Darioush Bijan Nejad   +3 more
doaj   +1 more source

Quercetin-loaded mesenchymal stem cell derived extracellular vesicles enhance ovarian function in a cyclophosphamide induced ovarian damage

Journal of Ovarian Research
Background To investigate whether intraovarian administration of quercetin-loaded extracellular vesicles derived from Wharton’s jelly mesenchymal stem cells (EVs-QUE) improves ovarian function in a cyclophosphamide (CTX)-induced premature ovarian ...
Zeynep Ece Utkan Korun, Zehra Seda Halbutogullari, Yusufhan Yazir, Selenay Furat, Candan Altuntas, Ahmet Ozturk, Tugba Koldankaya, Serap Mert, Erkut Attar   +8 more
doaj   +1 more source