Results 221 to 230 of about 62,645 (251)

Leptin biosynthetic pathway in white adipocytes

Biochemistry and Cell Biology, 2006
The aim of this study was to determine through morphological and biochemical means the biosynthetic and secretory pathway followed by leptin in adipocytes. Immunocytochemistry revealed the presence of leptin in the rough endoplasmic reticulum, the Golgi apparatus, and in numerous small vesicles along the plasma membrane of white adipo cytes. In vitro,
Philippe G, Cammisotto, Ludwik J, Bukowiecki, Yves, Deshaies, Moise, Bendayan   +3 more
openaire   +2 more sources

The histaminase activity of rat white adipocytes

Inflammation Research, 1997
Investigate the reaction conditions which allow the measurement of high affinity histamine oxidation.Isolated rat white adipocytes.The histaminase activity of rat white adipocytes and its inhibition by B24 and MDL 72274 was measured fluorimetrically or radiochemically in different experimental conditions.Histamine oxidation by rat white adipocytes is ...
RAIMONDI, L., BANCHELLI, G., PIRISINO, RENATO GIOVANNI PAOLO, IGNESTI, G., CONFORTI, L.   +4 more
openaire   +3 more sources

Serotonin prevents differentiation into brown adipocytes and induces transdifferentiation into white adipocytes

International Journal of Obesity, 2017
Serotonin is synthesized by many cells in the periphery to affect vasoconstriction, intestinal motility, and glucose and lipid metabolism. It has recently been shown that serotonin leads to fat accumulation in white adipose tissue (WAT). However, the direct effect of serotonin on brown adipose tissue differentiation and metabolism is limited. Therefore,
S, Rozenblit-Susan, N, Chapnik, O, Froy
openaire   +2 more sources

Mitophagy turns beige adipocytes white [PDF]

Nature Reviews Molecular Cell Biology, 2016
Katharine H Wrighton, Wrighton Katharine H   +1 more
exaly   +2 more sources

Proteomic differences between white and brown adipocytes

Amino Acids, 2014
Although a series of protein levels from several protein pathways have been shown to differ between white (WA) and brown (BA) adipocytes, proteomic work on this subject with the exception of mitochondrial protein differences is limited. It was, therefore, the aim of the study to compare WA with BA soluble protein levels. Proteins were extracted from WA
Wei-Qiang, Chen, Lin, Li, Gert, Lubec
openaire   +2 more sources

Voltage-Dependent Potassium Channels in White Adipocytes

Biochemical and Biophysical Research Communications, 1996
Macroscopic membrane currents of white adipocytes were studied using the whole-cell variant of the patch-clamp technique. These cells were obtained by differentiating preadipocytes fro rat epididymal tissue. In all differentiated cells outward currents exhibiting sigmoidal activation kinetics were observed with amplitudes ranging from 0.5 to 6 nA.
M P, Ramírez-Ponce, J C, Mateos, N, Carrión, J A, Bellido   +3 more
openaire   +2 more sources

Functional differentiation of white and brown adipocytes

BioEssays, 1997
AbstractAdipose tissue plays an important role in mammalian energy equilibrium not only as a lipid‐dissipating, i.e. energy‐storing, tissue (white adipose tissue), but also as an energy‐dissipating one (brown adipose tissue). Brown adipocytes have the ability of facultative heat production due to a unique mitochondrial protein, the uncoupling protein ...
openaire   +2 more sources

White adipocytes transdifferentiation into brown adipocytes induced by triiodothyronine

2008
The uncontrolled expansion of white adipose tissue (WAT) seen in obesity predisposes affected individuals to health complications. Another type of fat, brown adipose tissue (BAT) has an opposing physiological function because it allows dissipation instead of storage of energy.
A. Korac, M. Cakic-Milosevic, M. Ukropina, M. Grubic, K. Micunovic, V. Petrovic, B. Buzadzic, A. Jankovic, A. Vasilijevic, B. Korac   +9 more
openaire   +1 more source

Glucose Transport in White Adipocyte

2012
Adipocyte glucose transport is a key event for glucose homeostasis and is perturbed in insulin resistant situations like in obesity and type 2 diabetes. We will discuss how glucose transport is regulated in adipocyte, in normal, and in physiopathological conditions.
Mireille Cormont, Vincent Kaddai
openaire   +1 more source

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation

American Journal of Physiology - Endocrinology and Metabolism, 2010
The origin of brown adipocytes arising in white adipose tissue (WAT) after cold acclimatization is unclear. Here, we demonstrate that several UCP1-immunoreactive brown adipocytes occurring in WAT after cold acclimatization have a mixed morphology (paucilocular adipocytes).
Karsten Kristiansen, Saverio Cinti, Lise Madsen   +2 more
exaly   +6 more sources