Results 101 to 110 of about 388,905 (379)
Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023 This study performed a longitudinal analysis of a comprehensive panel of 22 innate and adaptive immune cell phenotypes, including differentiated and senescent CD4+ and CD8+ cells, with incident diabetes risk among a U.S. community‐based population of older adults.
Nels C. Olson +9 more
wiley +1 more source
Energy metabolism of white adipose tissue and insulin resistance in humans
European Journal of Clinical Investigation, 2018 Insulin resistance not only occurs in obesity, but also in lipodystrophy. Although adipose tissue mass affects metabolic fluxes and participates in interorgan crosstalk, the role of energy metabolism within white adipose tissue for insulin resistance is ...
K. Bódis, M. Roden
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.A magnetic microrobot fabricated by Spirulina platensis is proposed to accumulate in tumor regions and generate in situ high calcium concentration and sufficient oxygen. These characteristics of the microrobot present a strategy for triggering calcium overload therapy and chlorophyll‐mediated photodynamic therapy, and such combination resulted in a ...
Shuai Jiang +12 more
wiley +1 more source
Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023 Insulin resistance (IR) in adolescents with obesity is associated with a sex‐dependent metabolic “signature” comprising the branched‐chain amino acids (BCAAs), glutamate/glutamine, C3/C5 acylcarnitines, and uric acid. Here, we compared the levels of branched‐chain α‐keto acids (BCKAs) and glutamate/glutamine, which are byproducts of BCAA catabolism, as
Pinar Gumus Balikcioglu +8 more
wiley +1 more source
Cardiac Adipose Tissue Segmentation via Image-Level Annotations [PDF]
arXiv, 2022 Automatically identifying the structural substrates underlying cardiac abnormalities can potentially provide real-time guidance for interventional procedures. With the knowledge of cardiac tissue substrates, the treatment of complex arrhythmias such as atrial fibrillation and ventricular tachycardia can be further optimized by detecting arrhythmia ...
arxiv
Hypoxia and adipose tissue function and dysfunction in obesity [PDF]
, 2013 The rise in the incidence of obesity has led to a major interest in the biology of white adipose tissue. The tissue is a major endocrine and signalling organ, with adipocytes, the characteristic cell type, secreting a multiplicity of protein factors ...
Di Girolamo M +12 more
core +1 more source
Cecal Ligation and Puncture-Induced Sepsis Promotes Brown Adipose Tissue Inflammation Without Any Impact on Expression of Thermogenic-Related Genes [PDF]
, 2021 Background and Aims: The negative effects of chronic low-level inflammation on adipose tissue physiology have been extensively demonstrated, whereas the effects of acute inflammation are less studied.
Bouma, Hjalmar R. +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu +8 more
wiley +1 more source
Sparse multi-view matrix factorisation: a multivariate approach to multiple tissue comparisons [PDF]
, 2015 Gene expression levels in a population vary extensively across tissues. Such heterogeneity is caused by genetic variability and environmental factors, and is expected to be linked to disease development. The abundance of experimental data now enables the identification of features of gene expression profiles that are shared across tissues, and those ...
arxiv +1 more source
Plum pudding random medium model of biological tissue toward remote microscopy from spectroscopic light scattering [PDF]
Biomed. Opt. Express 8, 2879-2895 (2017), 2017 Biological tissue has a complex structure and exhibits rich spectroscopic behavior. There is \emph{no} tissue model up to now able to account for the observed spectroscopy of tissue light scattering and its anisotropy. Here we present, \emph{for the first time}, a plum pudding random medium (PPRM) model for biological tissue which succinctly describes ...
arxiv +1 more source