This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda +1 more
wiley +1 more source
Beta‐adrenergic agonist induces unique transcriptomic signature in inguinal white adipose tissue
Activation of thermogenic adipose tissue depots has been linked to improved metabolism and weight loss. To study the molecular regulation of adipocyte thermogenesis, we performed RNA‐Seq on brown adipose tissue (BAT), gonadal white adipose tissue (gWAT),
Henry A. Paz +5 more
doaj +1 more source
Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancy [PDF]
Obesity increases preeclampsia risk. Adipose tissue inflammation may contribute to the clinical syndrome of pre-eclampsia. We compared adipose tissue macrophage infiltration and release of pro-inflammatory adipokines in pre-eclampsia and healthy ...
Bray, Jack +6 more
core +1 more source
In vivo Analysis of White Adipose Tissue in Zebrafish [PDF]
White adipose tissue (WAT) is the major site of energy storage in bony vertebrates, and also serves central roles in the endocrine regulation of energy balance. The cellular and molecular mechanisms underlying WAT development and physiology are not well understood. This is due in part to difficulties associated with imaging adipose tissues in mammalian
James E N, Minchin, John F, Rawls
openaire +2 more sources
3D Printing Strategies for Bioengineering Human Cornea
This review highlights recent progress in 3D bioprinting strategies for engineering human corneas. Key aspects include the replication of corneal transparency, curvature, and biomechanical properties, alongside innovations in recent advancements in 3D printing methods, which benefit in overcoming current challenges.
Yunong Yuan +4 more
wiley +1 more source
White-to-Beige and Back: Adipocyte Conversion and Transcriptional Reprogramming
Obesity has become a pandemic, as currently more than half a billion people worldwide are obese. The etiology of obesity is multifactorial, and combines a contribution of hereditary and behavioral factors, such as nutritional inadequacy, along with the ...
Stanislav Boychenko +3 more
doaj +1 more source
Perivascular adipose tissue as a relevant fat depot for cardiovascular risk in obesity [PDF]
Obesity is associated with increased risk of premature death, morbidity, and mortality from several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD), myocardial infarction, and congestive heart failure.
Costa, Rafael M. +3 more
core +3 more sources
Mitochondrial function/dysfunction in white adipose tissue
New Findings What is the topic of this review?The review covers basic knowledge about the role of mitochondria in the homeostatic function of adipose tissue. It also provide a comprehensive analysis of how mitochondrial function is affected during obesity and lipoatrophies and discuss the results of recent studies that targeted mitochondrial function ...
Sihem, Boudina, Timothy E, Graham
openaire +2 more sources
Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar +7 more
wiley +1 more source
Thigh fat and muscle each contribute to excess cardiometabolic risk in South Asians, independent of visceral adipose tissue. [PDF]
OBJECTIVE: To compare fat distribution and associations between fat depots and cardiometabolic traits in South Asians and Europeans. METHODS: Five hundred and fourteen South Asians and 669 Europeans, aged 56-86.
Chaturvedi, N +8 more
core +1 more source

