Results 81 to 90 of about 257,277 (359)

Adipose-Derived Stem Cells: Isolation, Characterization, and Differentiation Potential

Cell Transplantation, 2013
In mammals, the two main types of adipose tissues, white and brown adipose tissues, exert different physiological functions. White adipose tissue (WAT) is for storing energy, while brown adipose tissue (BAT) is for energy consumption.
Shyh-Jer Huang, Ru-Huei Fu, Woei-Cherng Shyu, Shih-Ping Liu, Gwo-Ping Jong, Yung-Wei Chiu, Hsiao-Su Wu, Yung-An Tsou, Chao-Wen Cheng, Shinn-Zong Lin M.D., Ph.D.   +9 more
doaj   +1 more source

Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection

Cell Reports, 2019
Summary: Obesity in humans is associated with poorer health outcomes after infections compared with non-obese individuals. Here, we examined the effects of white adipose tissue and obesity on T cell responses to viral infection in mice.
Ichiro Misumi, Joshua Starmer, Toru Uchimura, Melinda A. Beck, Terry Magnuson, Jason K. Whitmire   +5 more
doaj   +1 more source

Twist1 in Human White Adipose Tissue and Obesity [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2011
Twist1 is a transcription factor implicated in the regulation of TNFα signaling and was recently shown to be highly expressed in both human and murine adipose tissue, but its role in obesity is unknown.Our objective was to assess the expression of twist1 in human white adipose tissue (WAT), its relationship to obesity and insulin sensitivity, and how ...
Amanda T, Pettersson, Niklas, Mejhert, Margareta, Jernås, Lena M S, Carlsson, Ingrid, Dahlman, Jurga, Laurencikiene, Peter, Arner, Mikael, Rydén   +7 more
openaire   +2 more sources

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source

Noggin depletion in adipocytes promotes obesity in mice. [PDF]

, 2019
ObjectiveObesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin ...
Blázquez-Medela, Ana M, Boström, Kristina I, Fogelman, Alan M, Guo, Yina, Jumabay, Medet, Lusis, Aldons J, Rajbhandari, Prashant, Reue, Karen, Sallam, Tamer, Tontonoz, Peter, Vergnes, Laurent, Wu, Xiuju, Yao, Jiayi, Yao, Yucheng, Zhang, Li   +14 more
core   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Perivascular adipose tissue as a relevant fat depot for cardiovascular risk in obesity [PDF]

, 2018
Obesity is associated with increased risk of premature death, morbidity, and mortality from several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD), myocardial infarction, and congestive heart failure.
Costa, Rafael M., Lobato, Núbia S., Neves, Karla B., Tostes, Rita C.   +3 more
core   +3 more sources

Hysteresis of White Adipose Tissue

Open Journal of Endocrine and Metabolic Diseases, 2015
no ...
Geloen, Alain, Soula, Hédi, Hadji, Lilas, Berger, Emmanuelle   +3 more
openaire   +4 more sources

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue. [PDF]

PLoS ONE, 2018
White adipose tissue expands through both adipocyte hypertrophy and hyperplasia and it is hypothesized that fibrosis or excess accumulation of extracellular matrix within adipose tissue may limit tissue expansion contributing to metabolic dysfunction ...
Mike Jager, Mi-Jeong Lee, Chendi Li, Stephen R Farmer, Susan K Fried, Matthew D Layne   +5 more
doaj   +1 more source