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White adipose tissue and cardiovascular disease

Best Practice & Research Clinical Endocrinology & Metabolism, 2005
Adipocytes have recently been shown to secrete a variety of bioactive substances called 'adipocytokines', and have been recognized as endocrine cells. Tumour necrosis factor (TNF)-alphaalpha, plasminogen activator inhibitor-1 (PAI-1) and heparin-binding epidermal-growth-factor-like growth factor (HBEGF) are among these adipocytokines, and they ...
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Explant Cultures of White Adipose Tissue

2008
Obesity is characterized by increased adiposity of visceral and subcutaneous depots as well as other organs, including the vasculature. These fat depots secrete various hormone-like proteins implicated in metabolic homeostasis (e.g., adiponectin, resistin), the central control of appetite (e.g., leptin) and the increased production of cytokines.
Sébastien, Thalmann   +2 more
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Sandwiched White Adipose Tissue: A Microphysiological System of Primary Human Adipose Tissue

Tissue Engineering Part C: Methods, 2018
White adipose tissue (WAT) is a critical organ in both health and disease. However, physiologically faithful tissue culture models of primary human WAT remain limited, at best. In this study we describe a novel WAT culture system in which primary human WAT is sandwiched between tissue-engineered sheets of adipose-derived stromal cells.
Frank H, Lau   +12 more
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Maintenance of white adipose tissue in man

The International Journal of Biochemistry & Cell Biology, 2014
Obesity is increasing in an epidemic manner in most countries and constitutes a public health problem by enhancing the risk for diseases such as diabetes, fatty liver disease and atherosclerosis. Together these diseases form a cluster referred to as the metabolic syndrome.
Mervi T. Hyv?nen, Kirsty L. Spalding
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Organ culture of rat white adipose tissue

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1972
Abstract 1. 1. Intact rat epididymal fat pads were incubated for up to 6 days in Trowell's medium with 20% fetal calf serum. Fat pad DNA content fell by 30% after 6 days of incubation. The lipid content of the incubated fat pads increased by 11% after 3 days of incubation and then remained constant.
J, Frohlich, A, Vost, C H, Hollenberg
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Organization of white adipose tissue in lemuridae

American Journal of Primatology, 1995
AbstractThe gross anatomy of white adipose tissue was studied in seven carcasses representing three lemurid species (Lemur catta, Eulemur fulvus, E. mongoz) to validate in vivo methods of assessing fatness, and to contribute to a comprehensive database on the organization of adipose tissue in Mammalia.
Michael E, Pereira, Caroline M, Pond
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Human White Adipose Tissue Metabolome: Current Perspective

Obesity, 2018
ObjectiveInterest in metabolites produced by adipose tissue has increased substantially in the past several decades. Previously regarded as an inert energy storage depot, adipose tissue is now viewed as a complex metabolically active organ with considerable impact on human health.
Jan, Kučera   +5 more
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Autophagy in White Adipose Tissue

2014
Autophagy is a mechanism for intracellular degradation of cytoplasmic components including macromolecules and organelles. It has been shown to be involved in a large number of physiological and pathological processes. Studies have recently uncovered an important role of autophagy in the process of adipogenesis.
Scott G. Goldman   +2 more
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MHO or MUO? White adipose tissue remodeling

Obesity Reviews
SummaryIn this review, we delve into the intricate relationship between white adipose tissue (WAT) remodeling and metabolic aspects in obesity, with a specific focus on individuals with metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO).
Jing Yi Zhao   +4 more
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