Peri‐ and Post‐Menopausal Hormone Replacement Therapy and Voice Disorder Risk: A TriNetX Study
ABSTRACT Objectives The aim of this study was to elucidate the risk of developing voice disorders among peri‐ and post‐menopausal female hormone replacement therapy (HRT) users. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network.
David Kayekjian +4 more
wiley +1 more source
WDR4-mediate tRNA m7G modification to promote mitophagy and browning of white adipose tissue for ameliorating obesity in male mice. [PDF]
Lin B +6 more
europepmc +1 more source
Elevated BMI Is Not Associated With Adverse Outcomes in Open Airway Reconstruction
ABSTRACT Background Open airway reconstruction is indicated for structural airway stenoses but may be associated with significant morbidity. While obesity influences perioperative outcomes in many surgical domains, its role in airway reconstruction remains unclear.
Dylan Bertoni +3 more
wiley +1 more source
Obesity, White Adipose Tissue, and Adipokines Signaling in Male Reproduction. [PDF]
Martins FF +6 more
europepmc +1 more source
ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud +2 more
wiley +1 more source
Obesity drives depot-specific vascular remodeling in male white adipose tissue. [PDF]
Hasan SS +15 more
europepmc +1 more source
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei +9 more
wiley +1 more source
BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue. [PDF]
Sieckmann K +23 more
europepmc +1 more source
Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang +9 more
wiley +1 more source
Molecular mechanisms of propolis in adipogenesis, lipid metabolism and white adipose tissue Browning: a systematic review of preclinical studies. [PDF]
Megantara I +4 more
europepmc +1 more source

