Results 221 to 230 of about 257,277 (359)

PSPC1-SMAD3 axis regulates iron-induced beiging of adipocytes in white adipose tissue. [PDF]

Cell Commun Signal
Peng XM, He R, Wang HY, Liu JD, Xie YY, Wang ZH, Deng HY, Wang WS, Zhu ZZ, Ge J, Liu YL, Gao RH, Yang M, Li DP, Kang QQ, Pan RP, Chen Y.   +16 more
europepmc   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

White adipose tissue browning and peroxisome proliferator activated receptors in MASLD. [PDF]

Front Endocrinol (Lausanne)
Li Z, Chu H, Yang L.
europepmc   +1 more source

Skeletal muscle tissue secretes more extracellular vesicles than white adipose tissue and myofibers are a major source ex vivo but not in vivo [PDF]

, 2020
Andrea Estrada, Zackary J. Valenti, Gabriella Hehn, Chris Allen, Nicole A. Kruh‐Garcia, Daniel S. Lark   +5 more
openalex   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

The liver clock modulates circadian rhythms in white adipose tissue. [PDF]

Mol Metab
Vlassakev I, Savva C, Renzi G, Ilamathi HS, Mamand DR, Smith JG, Greco CM, Litwin C, Zhang Q, Velez L, Ma A, Bergo MO, Wiklander OPB, Muñoz-Cánovez P, Mejhert N, Seldin M, Björkegren JLM, Sassone-Corsi P, Koronowski KB, Benitah SA, Petrus P.   +20 more
europepmc   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

KBN2202 Suppresses Gonadal White Adipose Tissue Expansion in Female Mice Fed a High-Fat Diet. [PDF]

Int J Mol Sci
Kim M, Heo JH, Chang SH, Lee SY, Kim J, Shin MG, Kim JS, Choi MR, Lee SR.   +8 more
europepmc   +1 more source

The gut microbiota modulates the white adipose tissue functional remodeling

, 2018
Nicolas Suarez Zamorano
openalex   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source