JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Adrien Boyard +12 more
wiley +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
White Matter Hyperintensities and Neuropsychiatric Symptoms in Neurodegenerative Diseases. [PDF]
Katakami S +13 more
europepmc +1 more source
Abstract Advanced age is the strongest risk factor for Alzheimer's disease and related dementias (ADRDs). Traumatic brain injury (TBI) has also been recognized as a risk factor for ADRD, potentially contributing to an earlier onset of the disease. Thus, elucidating the mechanisms underlying brain ageing and TBI is critical for developing strategies to ...
Tsubasa Tomoto +3 more
wiley +1 more source
Dorsal ischaemic myelopathy in a dog: A case of unilateral, focal predominantly sensory loss
Abstract A 3‐year‐3‐month‐old, neutered, male Great Dane was presented with peracute left hindlimb monoparesis. Although voluntary movement was present, the dog was effectively non‐ambulatory due to its size. Proprioception, nociception and spinal reflexes were absent in the left hindlimb, localising the lesion to a left L4–S1 myelopathy.
Alexandra Ayoub +3 more
wiley +1 more source
Erratum: U-fiber analysis: a toolbox for automated quantification of U-fibers and white matter hyperintensities. [PDF]
Editorial Office.
europepmc +1 more source
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Glymphatic dysfunction associates with regional white matter hyperintensities and plasma amyloid-β burden across the Alzheimer's disease continuum. [PDF]
Chen HJ +5 more
europepmc +1 more source
Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley +1 more source
Correction to "White matter hyperintensities are associated with locus coeruleus atrophy and astrocytic β2-adrenergic receptor expression". [PDF]
europepmc +1 more source

