Results 181 to 190 of about 25,224 (259)

Rare Biallelic CTU2 Variants in an Individual With CAKUT: Clinical Characterization and Minigene Splicing Analysis

Molecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.
Exome sequencing in 200 CAKUT patients identified compound heterozygous rare CTU2 variants in one renal‐predominant case. Minigene splicing assays showed c.913C>T partially increased exon 9 skipping, supporting further case collection and kidney‐relevant studies to clarify the role of CTU2 in renal developmental phenotypes.
Qian Liu, Xueqin Cheng, Bixia Zheng, Chunli Wang, Wei Zhou, Aihua Zhang   +5 more
wiley   +1 more source

Standard Model Imaging in the Brain and Spinal Cord of MS Patients: Initial Assessment and Comparison to Diffusion Tensor Imaging

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
DTI and SMIfw diffusion models applied in persons with multiple sclerosis revealed region‐specific sensitivity to microstructural injury, but performance differed by anatomical region. SMIfw neurite density fraction demonstrated high sensitivity and reliability in both the brain and spinal cord, whereas DTI measures such as fractional anisotropy and ...
Atlee Witt, Alicia E. Cronin, Bailey Busher, Isabella Stuart, Grace Sweeney, Kristin P. O'Grady, Seth A. Smith, Samantha By, Kurt Schilling   +8 more
wiley   +1 more source

Unusual MRI features in a case of presumed canine tick‐borne meningoencephalomyelitis

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 7‐year‐old, standard, wire‐haired dachshund presented with quickly progressive multifocal central nervous system signs, which localised to the brainstem and cervical myelopathy, including reduced cervical and thoracic limb muscle tone and withdrawal reflexes. Magnetic resonance imaging revealed bilateral, approximately symmetric, T2‐weighted
Jon Prager, Alex Smith, Hélène Vandenberghe   +2 more
wiley   +1 more source

Effects of Physical Activity on Brain White Matter Integrity Are Region‐, Dose‐, and Age‐Dependent: Findings From the Population‐Based Rhineland Study

Aging Cell, Volume 25, Issue 8, August 2026.
Physical activity is related to more aligned white matter fibers and microstructural reorganization of the brain. Body weight, cardiometabolic, and inflammatory factors could partly mediate the effects of physical activity on brain white matter microstructure. The effects of physical activity on the brain are age‐ and region‐specific.
Eva Saxler, Fabienne A. U. Fox, Alexandra Koch, Xingwang Yang, Weiyi Zeng, Santiago Estrada, Monique M. B. Breteler, N. Ahmad Aziz   +7 more
wiley   +1 more source

A Rare Overlap of AQP4 and MOG Seropositivity in Neuromyelitis Optica Spectrum Disorder: A Case Report

Clinical and Experimental Neuroimmunology, Volume 17, Issue 3, August 2026.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is an immune‐mediated disorder of the central nervous system associated with autoantibodies against aquaporin‐4 (AQP4). This is distinct from myelin‐oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), defined by anti‐MOG antibodies.
Sarah E. Butler, Siew Kar Chen, Mastura Monif   +2 more
wiley   +1 more source

Longitudinal retinal microvascular changes and their association with white matter hyperintensities in neuromyelitis optica spectrum disorder. [PDF]

Front Neurol
Liu Y, Xu S, Lin H, Lei X, Li Y, Xu Z, Wei R, Jiang HR, Mei J.   +8 more
europepmc   +1 more source

Association of Long‐Term Trajectories in Obesity Indices With Neuroimaging Metrics and Cognition: A Population‐Based Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7562-7579, August 2026.
ABSTRACT Objective Accurate assessment of gradual age‐related weight gain, a common phenomenon, is crucial for identifying brain health risks. This study investigated the associations between long‐term trajectories in obesity indices and brain structure and cognition. Methods This study included 1114 participants from the Kailuan cohort with ≥ 3 follow‐
Yanbo Liang, Zhiming Lu, Xiaoqing Yuan, Mingze Xu, Ying Hui, Shouling Wu, Zhenchang Wang, Ning Wu, Yuntao Wu, Han Lv   +9 more
wiley   +1 more source