Results 191 to 200 of about 4,691,212 (288)

Coronary artery disease and cardiac pathology in cerebral small vessel disease and post‐stroke dementia: Implications for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 11, November 2026.
Abstract BACKGROUND The relationships between coronary or cardiac pathology, cerebral small vessel disease (SVD), Alzheimer's disease pathology, and vascular cognitive impairment and dementia (VCID) remain unclear. METHODS We performed a clinicopathological study in 75 stroke patients enrolled in the prospective Cognitive Function After Stroke (CogFAST)
Yoshiki Hase, Tuomo Polvikoski, Dan Jobson, Klarizze Premarion, Ethan Tutter, Erika Kitajima, Pazhanichamy Kalailingam, Xavier Gallart‐Palau, Siu Kwan Sze, Louise Allan, Raj N. Kalaria   +10 more
wiley   +1 more source

Systemic Inflammation and White Matter Hyperintensities Associated with Cognitive Impairment in Intracranial Atherosclerotic Stenosis: A Retrospective Observational Study. [PDF]

J Inflamm Res
Huang ZR, Pan HT, Liu CC, Wang SW, Guo X, Liu YA, Huang LX, Fan SY, Wu XB, Zheng MG, Luo B.   +10 more
europepmc   +1 more source

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community

Annals of Neurology, Volume 100, Issue 5, Page 987-997, November 2026.
Objective We aimed to investigate the associations between Alzheimer's disease (AD)‐related blood biomarkers and changes in brain volumes and cerebrovascular burden in community‐dwelling older adults. Methods We included 361 dementia‐free participants with a Mini‐Mental State Examination (MMSE) score ≥ 27 and without prior cerebrovascular events from a
Martina Valletta, Davide Liborio Vetrano, Erika J. Laukka, Grégoria Kalpouzos, Javier Oltra, Debora Rizzuto, Marco Canevelli, Claudia Fredolini, Chengxuan Qiu, Bengt Winblad, Laura Fratiglioni, Giulia Grande   +11 more
wiley   +1 more source

Topography of Juxtaventricular white matter hyperintensities and cognitive associations in Alzheimer's disease: a dual-cohort study. [PDF]

Eur Radiol Exp
Bao YW, Ji YQ, Wang LN, Zhou Y, Wang F, Shen DM, Pylypenko D, Tong Q, Mak KF, Guo LL.   +9 more
europepmc   +1 more source

Multimodal Characterization of Glymphatic‐Related Magnetic Resonance Imaging Markers in Huntington's Disease: A Multi‐Cohort Retrospective Study

Annals of Neurology, Volume 100, Issue 5, Page 1055-1067, November 2026.
Objective To characterize magnetic resonance imaging (MRI)‐based glymphatic surrogates in Huntington's disease (HD) using MRI measures of perivascular diffusivity and structural perivascular alterations across multiple large cohorts. Methods We analyzed 2,731 MRI sessions from 880 participants across 3 large retrospective HD cohorts.
Alexia Solomon, Zexi Wang, Francesco Sanvito, Zheng Zhou, Adys Mendizabal, Jingwen Yao   +5 more
wiley   +1 more source

Norms for Automatic Estimation of White Matter Hyperintensities Burden: LST-AI Service in neuGRID. [PDF]

Diagnostics (Basel)
Boccali A, De Francesco S, Crema C, Demaria C, Baronio CM, Archetti D, Redolfi A.   +6 more
europepmc   +1 more source

A Multimodal Neuroimaging Study of Hyperlipidemia‐Induced Abnormal Spontaneous Brain Activity and Cognitive Decline

Brain and Behavior, Volume 16, Issue 11, November 2026.
ABSTRACT Objective To investigate multidomain cognitive performance in older adults with hyperlipidemia and its associations with alterations in spontaneous brain activity and functional connectivity (FC). Methods A total of 104 participants were recruited, comprising 50 hyperlipidemia patients and 54 healthy controls.
Jian‐Hui He, Jia‐Jia Wu, Fan‐Long Meng, Yun‐Ting Xiang, Rong‐Rong Huang, Mou‐Xiong Zheng, Jie Ma, Jian‐Guang Xu   +7 more
wiley   +1 more source

Diffusion-weighted imaging reversal after reperfusion therapy in acute ischemic stroke: associations with white matter hyperintensities and cerebral microbleeds. [PDF]

Neurol Res Pract
Bannert N, Klassen P, Krijatov R, Dooat A, Nosanova A, Dreyhaupt J, Müller HP, Haeusler KG, Laible M.   +8 more
europepmc   +1 more source

Prenatal Diagnosis of Recurrent Fetal Intracranial Hemorrhage and a Maternally Inherited COL4A1 Variant of Uncertain Significance: A Case Report With Maternal Reverse Phenotyping

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT A 33‐year‐old woman with two consecutive pregnancies affected by fetal left periventricular germinal matrix hemorrhage (Grade IV) and progressive ventriculomegaly underwent trio whole‐exome sequencing. A heterozygous COL4A1 c.4249G>C (p.Gly1417Arg) variant, classified as a variant of uncertain significance, was identified in the fetus of the ...
Wei Shi, Hongjing Xu, Caihong Pu, Yuanzhong Liang, Ting Zhao, Xueli Wang, Zhenxing Liu, Chunhua Zhang, Ting Li, Fengquan He   +9 more
wiley   +1 more source

Possible Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS) Presenting in Late Adolescence and Early Adulthood: A Case Series

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT PANDAS‐like syndromes may rarely occur beyond childhood. Although these patients may meet criteria for PANS, recognizing a possible streptococcal‐triggered subgroup remains important for diagnosis, future biomarker discovery, and refinement of disease classification.
Tariq A. Madani, Fahd S. Alsallum, Ola H. Abudaowd, Salman T. Madani   +3 more
wiley   +1 more source