Results 191 to 200 of about 25,095 (260)

Cortical gray–white matter contrast alterations precede amyloid‐β positivity and macrostructural changes in older adults without dementia

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Early Alzheimer's disease (AD) involves subtle cortical changes that may precede atrophy. Magnetic resonance imaging (MRI) microstructural markers may detect earlier pathology than classical morphometry. METHODS We analyzed cross‐sectional MRI and amyloid‐β (Aβ) positron emission tomography (PET) data from 1323 non‐demented AMYPAD
Leonard Pieperhoff, Luigi Lorenzini, Francisco Almeida, Mario Tranfa, Ariane Bollack, Prithvi Arunachalam, Federico Masserini, Robin Wolz, Sylke Grootoonk, Craig Ritchie, Mercè Boada, Marta Marquié, Jort Vijverberg, Rik Vandenberghe, Bernard J. Hanseeuw, Pablo Martinez‐Lage, Pierre Payoux, Pieter Jelle Visser, Michael Schöll, Giovanni B. Frisoni, Matteo Pardini, Luca Roccataglia, Andrew W. Stephens, Chris Buckley, Gill Farrar, Frank Jessen, Juan Domingo Gispert, Gemma Salvadó, Emma S. Luckett, Henk‐Jan MM Mutsaerts, Alle Meije Wink, Lyduine E. Collij, Frederik Barkhof, Tiago Gil Oliveira, the AMYPAD consortium   +34 more
wiley   +1 more source

Heterogeneity of white matter hyperintensities in Alzheimer's disease captured by multimodal neuroimaging. [PDF]

Sci Rep
Garnier-Crussard A, Landeau B, Mezenge F, Gonneaud J, Roquet D, Cotton F, Chetelat G.   +6 more
europepmc   +1 more source

Prevalence and Risk Factors for Cerebral Microbleeds in Chinese Patients With Acute Ischemic Stroke

Brain and Behavior, Volume 16, Issue 6, June 2026.
Approximately half of the patients with AIS exhibited CMBs, particularly those classified under LAA and SVD subtypes. Hypertension and severe WMH were independently associated with CMB presence. Distinct clinical profiles were observed based on CMB burden and location.
Ruiming Zhu, Yinglin Yang, Xiaoyan Chen, Lei Hou, Xiangshu Cheng, Mianwang He   +5 more
wiley   +1 more source

A study on the correlation between APOE gene polymorphism, white matter hyperintensities, and neuropsychiatric symptom phenotypes in Alzheimer's disease. [PDF]

Front Psychiatry
Fan W, Wang Z, Wan S, Liu M, Han Y, Liu X, Xu L, Wang X, Zhang D, Cai Q.   +9 more
europepmc   +1 more source

Falls and Fear of Falling in Minor Stroke Patients With Vestibular Symptoms: A Longitudinal Observational Study

Brain and Behavior, Volume 16, Issue 6, June 2026.
This prospective study reveals that persistent vestibular symptoms, cerebral small vessel disease, and anxiety/depression predict long‐term fall risk in minor stroke patients. Early identification and intervention within the first 3 months poststroke may help mitigate balance impairment and improve outcomes.
Yao Zhong, Jiaokun Jia, Jiashu Li, Ruixuan Jiang, Xingquan Zhao, Yi Ju   +5 more
wiley   +1 more source

Mitigating disparities in diagnosis of dementia

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract The field of Alzheimer's disease and related dementias (AD/ADRD) is undergoing a transformative shift with a better understanding of disease biology, biomarker‐based diagnostics, and disease‐modifying therapies. Yet, these advancements risk exacerbating existing disparities in diagnosis and care.
Lycia Tramujas Vasconcellos Neumann, Simin Mahinrad, Erin Abner, Soo Borson, Goldie S. Byrd, Maria C. Carrillo, Lindsay Clark, Anthony N. Correro II, Kacie D. Deters, Peggye Dilworth‐Anderson, Rebecca M. Edelmayer, Jason D. Flatt, Crystal M. Glover, Joshua D. Grill, Carl V. Hill, Thomas K. Karikari, Fred B. Ketchum, Emily A. Largent, Jennifer H. Lingler, Jose A. Luchsinger, Gladys E. Maestre, Michelle M. Mielke, Sid O'Bryant, Ozioma C. Okonkwo, Monica W. Parker, Annalise M. Rahman‐Filipiak, Rema Raman, Suzanne E. Schindler, Jose Soria Lopez, Shana D. Stites, Astrid M. Suchy‐Dicey, Whitney Wharton, Rachel A. Whitmer, Lisa Ann Kirk Wiese, Charles C. Windon, Amy Kind, Lisa L. Barnes   +36 more
wiley   +1 more source

A Diagnostic Challenge: From Suspected Ischemic Stroke to Confirmed Herpetic Encephalitis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Multimodal neuroimaging in a case of HSV‐1 encephalitis mimicking malignant MCA stroke: from initial CT findings misinterpreted as large territorial infarction, through decompressive craniectomy for refractory intracranial hypertension, to MRI confirmation of non‐territorial haemorrhagic encephalitis prompting CSF analysis and acyclovir therapy ...
Mafalda Dias Neves, Miguel Gonçalves Pereira, Natacha Silveira, Susana Barbosa, José Maria Matos Sousa, Eduarda Pereira, Elisabete Monteiro   +6 more
wiley   +1 more source

Quantifying White Matter Hyperintensities: Automated Volumetry Compared with Visual Grading Scales. [PDF]

Medicina (Kaunas)
Titovs A, Šilovs A, Kaļva K, Platkājis A, Kostiks A, Šneidere K, Karelis G, Stepens A, Zdanovskis N.   +8 more
europepmc   +1 more source