Results 211 to 220 of about 4,691,212 (288)

Erratum: U-fiber analysis: a toolbox for automated quantification of U-fibers and white matter hyperintensities. [PDF]

Quant Imaging Med Surg
Editorial Office.
europepmc   +1 more source

Dorsal ischaemic myelopathy in a dog: A case of unilateral, focal predominantly sensory loss

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 3‐year‐3‐month‐old, neutered, male Great Dane was presented with peracute left hindlimb monoparesis. Although voluntary movement was present, the dog was effectively non‐ambulatory due to its size. Proprioception, nociception and spinal reflexes were absent in the left hindlimb, localising the lesion to a left L4–S1 myelopathy.
Alexandra Ayoub, Ana Maria Oliveira, Nicholas Goody, Aran Nagendran   +3 more
wiley   +1 more source

Structural Brain Pathways Linking White Matter Hyperintensities to Pain Sensitivity

Liu X, Vangberg TR, Kuiper LM, Vernooij MW, Stubhaug A, Steingrímsdóttir ÓA, Page CM, Nielsen CS, van Meurs JBJ, Roshchupkin GV.   +9 more
europepmc   +1 more source

Glymphatic dysfunction associates with regional white matter hyperintensities and plasma amyloid-β burden across the Alzheimer's disease continuum. [PDF]

Psychol Med
Chen HJ, Guo Y, Huang W, Hu A, Liu T, Chen F.   +5 more
europepmc   +1 more source

Clinical and MRI findings of suspected cerebrospinal nematodiasis in an alpaca

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 5‐year‐old alpaca was presented with a 2‐week history of progressive pelvic limb ataxia and paresis. Neurological examination localised the lesion to the thoracolumbar spinal cord. Magnetic resonance imaging (MRI) of the cervical and thoracolumbar spine revealed no abnormalities; however, contrast‐enhanced sequences were not performed due to
Aurelia Gasser, Mireille Meylan, Alexane Durand, Veronika Stein, Arianna Maiolini   +4 more
wiley   +1 more source

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

Brain Pathology, Volume 36, Issue 6, November 2026.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, Pedro González, Luis Jiménez‐Roldán, Guillermo García‐Posadas, Aurelio Hernández‐Laín, Ángel Pérez‐Núñez, Pilar Sánchez‐Gómez   +18 more
wiley   +1 more source

Dysregulated TIE‐2 expression is associated with blood‐brain barrier leakiness and Alzheimer's disease‐related neuropathology

Brain Pathology, Volume 36, Issue 6, November 2026.
Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Carey Gleason, Barbara B. Bendlin, Ozioma Okonkwo, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson, Seth Love, J. Scott Miners   +12 more
wiley   +1 more source

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

Brain Pathology, Volume 36, Issue 6, November 2026.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle, Isabella Boesgaard, Austyn Roseborough, Meaghan Frank, Qi Zhang, Stephen H. Pasternak, Robert Hammond, Shawn N. Whitehead   +7 more
wiley   +1 more source

Subclinical Cerebral Lesions in Migraine: A Proof‐of‐Concept Study on Platelet Aggregation

European Journal of Neurology, Volume 33, Issue 11, November 2026.
We assessed platelet aggregation in patients with migraine (n = 34) with or without cerebral white‐matter lesions (WMLs) versus matched controls (n = 34), with WMLs volume quantified by MRI (mm3). Aggregation to ADP, collagen, epinephrine, and arachidonic acid was measured; epinephrine‐induced aggregation at 1.25–2.5 μM was overall lower in migraine ...
Ilaria Maestrini, Mariaignazia Curreli, Marta Puma, Costanza Giannì, Eleonora Schiera, Giada Giuliani, Massimiliano Toscano, Marta Altieri, Patrizia Pantano, Fabio Pulcinelli, Vittorio Di Piero   +10 more
wiley   +1 more source

Recognising Mild Cognitive Impairment and Early Alzheimer's Disease in General and Psychiatric Practice: Clinical Clues and Appropriate Referral

Psychogeriatrics, Volume 26, Issue 6, November 2026.
ABSTRACT Early cognitive decline may become evident through changes in daily activities or behaviour before it is apparent in a brief consultation. This selective narrative review supports case‐finding and appropriate referral in general and psychiatric practice.
Kengo Shimoda
wiley   +1 more source