Results 201 to 210 of about 4,691,212 (288)

Therapeutic Reversal of Severe Neuropsychiatric Symptoms in Wilson's Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Wilsons disease is an autosomal recessive genetic disorder of copper metabolism that results in copper accumulation in liver and other organs. Hepatic manifestation tends to occur earlier than the neurological manifestation. We present a case with psychiatric presentation.
Tshering Penjor, Sangay Dorji, Sonam Wangchuk   +2 more
wiley   +1 more source

Correction to "White matter hyperintensities are associated with locus coeruleus atrophy and astrocytic β2-adrenergic receptor expression". [PDF]

Alzheimers Dement
europepmc   +1 more source

White Matter Hyperintensities and Neuropsychiatric Symptoms in Neurodegenerative Diseases. [PDF]

J Clin Neurol
Katakami S, Kanemoto H, Taomoto D, Satake Y, Suehiro T, Sato S, Yoshiyama K, Kashibayashi T, Takahashi R, Tagai K, Shinagawa S, Ishii K, Kazui H, Ikeda M.   +13 more
europepmc   +1 more source

Pregnancy‐Induced Hypertension Complicated by Posterior Reversible Encephalopathy Syndrome: A Case Series of Two Patients

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Posterior reversible encephalopathy syndrome (PRES) is a rare but potentially life‐threatening neurological complication associated with hypertensive disorders of pregnancy. This report presents two cases of pregnancy‐induced hypertension complicated by PRES, both clinically characterized by headache and visual disturbances, with ...
Xintong Zhao, Mengqing Yan, Feixiang Long, Androniks Mumdzjans, Rongrong Song   +4 more
wiley   +1 more source

Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance. [PDF]

Nat Commun
Menze I, Bernal J, Kievit RA, Tripathi KP, Kaleck T, Yakupov R, Altenstein S, Bartels C, Buerger K, Butryn M, Dechent P, Ewers M, Fliessbach K, Frommann I, Gemenetzi M, Glanz W, Gref D, Hellmann-Regen J, Hetzer S, Incesoy EI, Janowitz D, Kiliman I, Kleineidam L, Kronmüller MT, Laske C, van Lent DM, Lüsebrink F, Perneczky R, Peters O, Preis L, Priller J, Rauchmann BS, Rostamzadeh A, Roeske S, Scheffler K, Schott BH, Schneider A, Sodenkamp S, Spottke A, Spruth EJ, Stark M, Teipel S, Wagner M, Wiltfang J, Jessen F, Ramirez A, Schreiber S, Düzel E, Ziegler G.   +48 more
europepmc   +1 more source

Alzheimer's Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 11, November 2026.
Alzheimer's disease involves Aβ/tau aggregation, neuroinflammation, BBB leakage, gut–brain dysfunction, and mitochondrial damage, causing neuronal loss. Nanodelivery enables combined small‐molecule and targeted therapies. Disease‐modifying biologics/chemicals, including anti‐Aβ antibodies, raise safety and access concerns. Exercise, cognitive training,
Gaoshuang Fu, Mingmin Pan, Qingling Sun, Guangxin Yue, Tong Lei   +4 more
wiley   +1 more source

Atherosclerosis: From Pathogenesis to Therapeutic Interventions

MedComm, Volume 7, Issue 11, November 2026.
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou, Chenxi Zhan, Yuting Li, Yi Zeng, Renfei Luo, Xin Ouyang, Shixing Liu, Renqiang Yang, Nianlong Yan, Long Jiang   +9 more
wiley   +1 more source

Visual rating versus volumetric segmentation of white matter hyperintensities for cognitive assessment: a memory clinic-based comparison and systematic review. [PDF]

Cereb Circ Cogn Behav
van Dijk GGCEA, Box CVJ, Faghir F, Martens J, Papma JM, Mattace Raso FUS, Berg EVD, Vernooij MW, Wolters FJ.   +8 more
europepmc   +1 more source

Volumetric and Intrastructural Characterization of the Substantia Nigra Using Optimized Synthetic MR Images Derived From Quantitative T1 Maps at 3 T

NMR in Biomedicine, Volume 39, Issue 11, November 2026.
Automated segmentation using the NextBrain atlas and synthetic MRI effectively overcomes systematic age‐related biases observed in manual delineation of the substantia nigra. A novel qT1‐based synthetic contrast utilizing signal‐increased pseudo‐proton spin density (pPSD) provides improved intrastructural separation of nigral subregions (SNpc and SNpr)
Lukas von Erdmannsdorff, Lora Kovacheva, Dennis C. Thomas, Elke Hattingen, Ralf Deichmann, Christophe Théo Arendt   +5 more
wiley   +1 more source