Results 81 to 90 of about 4,691,212 (288)

Alterations in structural integrity of superior longitudinal fasciculus III associated with cognitive performance in cerebral small vessel disease

BMC Medical Imaging
Background This study aimed to investigate the alterations in structural integrity of superior longitudinal fasciculus subcomponents with increasing white matter hyperintensity severity as well as the relationship to cognitive performance in cerebral ...
Yifan Wang, Tianyao Wang, Zekuan Yu, Junjie Wang, Fang Liu, Mengwen Ye, Xianjin Fang, Yinhong Liu, Jun Liu   +8 more
doaj   +1 more source

The relationship between cerebral microbleeds (CMBs) and white matter hyperintensities.

, 2014
The proportion of patients with CMBs increased with the severity of deep white matter hyperintensities (DWMH ...
Zhenfu Wang (534666), Mei Gong (534668), Weiping Wu (534670), Xiaobing Shi (534669), Yaner Guo (534667), Ningyu An (531778), Wei Wang (17594), Yanchang Shang (70702), Xian Xu (119341), Zhongbao Gao (534665), Xingli Zhao (294086), Lijuan Yang (1538233)   +11 more
core   +1 more source

Hyper‐Intense Tumor Peripheral Accumulation of Antibody‐Conjugated Iron Oxide Nanoparticles can Enable Breast Cancer Detection by Magnetic Particle Imaging

Advanced Science, EarlyView.
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath, Hayden Carlton, Theresa Wong, Sean Healy, Toby Sanders, Mason Song, Patrick W. Goodwill, Cordula Grüttner, Kathleen Gabrielson, Robert Ivkov   +9 more
wiley   +1 more source

White matter asymmetries in patients with cerebral small vessel disease [PDF]

Journal of Integrative Neuroscience, 2018
White matter asymmetries of the human brain have been well documented using diffusion tensor imaging. The purpose of this study was to investigate white matter asymmetry across the whole brain in cerebral small vessel disease patients and evaluate the ...
Hua Zhou, Yan Tang, Zhi Yuan
doaj   +1 more source

Left frontal white matter hyperintensities and choice RT intraindividual variability (women only).

, 2013
Left frontal white matter hyperintensities and choice RT intraindividual variability (women only).
Wei Wen (158865), Helen Christensen (64840), David Bunce (302457), Nicolas Cherbuin (333502), Perminder S. Sachdev (158912), Richard Burns (360702), Kaarin J. Anstey (333505)   +6 more
core   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

Cerebral Hemodynamic Changes in Older Adults With Cognitive Complaints According to the Presence of Peripheral Artery Disease

AGING MEDICINE, EarlyView.
Among 132 older adults, 13 had peripheral artery disease (PAD), identified using the ankle–brachial index. Over approximately 13 months, PAD was associated with increasing middle cerebral artery mean flow velocity, with a significant difference in left‐sided velocity change between groups.
SangMi Noh, Hae‐Eun Shin, YongSoo Shim
wiley   +1 more source

Binary logistic regression analysis with progression of white matter hyperintensities as dependent variable.

, 2016
Binary logistic regression analysis with progression of white matter hyperintensities as dependent variable.
Ellen C. van Overbeek (583776), Robert J. van Oostenbrugge (313470), Julie Staals (334771), Iris L. H. Knottnerus (348910), Hugo ten Cate (280615)   +4 more
core   +1 more source

AI‐Based Mitochondrial Network Characterization as a Biomarker for DNM1L‐Related Disease Diagnosis

Advanced Intelligent Systems, EarlyView.
This work provides proof‐of‐concept that AI‐based analysis of mitochondrial network morphology in patient‐derived fibroblasts can identify a phenotypic signature associated with DNM1L deficiency. This automated approach may ultimately provide a complementary functional readout for the interpretation of novel DNM1L variants following genetic testing ...
Uliana Musokhranova, Ioannis Georvasilis, Sofía Illescas, Matina Saritzoglou, Marcos Frías, Mònica Roldán, Anna Ardissone, Isabella Moroni, Àngels García‐Cazorla, Alfonso Oyarzábal   +9 more
wiley   +1 more source

White matter hyperintensities are positively associated with cortical thickness in Alzheimer's disease.

, 2014
White matter hyperintensities are associated with an increased risk of Alzheimer's disease (AD). White matter hyperintensities are believed to disconnect brain areas.
Jacobs, Heidi I. L., Aalten, Pauline, Aalten, P., Pauline Aalten, Clerx, Lies, Verhey, Frans R. J., Jacobs, Heidi, Ed H.B.M. Gronenschild, Clerx, L., Verhey, F. R. J., Lies Clerx, Gronenschild, E. H. B. M., Heidi I.L. Jacobs, Frans R.J. Verhey, Gronenschild, Ed H. B. M.   +14 more
core   +1 more source