Results 101 to 110 of about 40,902 (288)
Arquivos de Neuro-Psiquiatria, 2001 É relatado em alguns estudos que idosos deprimidos apresentam maior frequência de hipersinais ao exame de ressonância magnética do que controles normais. No entanto os indivíduos estudados tinham fatores de risco para doenças cerebrovasculares.
Tânia Maria da Silva Novaretti +5 more
doaj +1 more source
Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke [PDF]
, 2014 Aims: Cerebral small vessel disease (SVD) causes a fifth of all strokes plus diffuse brain damage leading to cognitive decline, physical disabilities and dementia.
Bailey, Emma L. +8 more
core +2 more sources
Animal Models and Experimental Medicine, EarlyView.We established a graded spinal cord injury (SCI) model based on graduated impact depth, which was subsequently characterized across multiple dimensions, including locomotor function, imaging, histology, and transcriptomic profiles. We further identified transcriptomic changes in graded SCI at different time points postinjury and investigated the ...
Gang Zhou +6 more
wiley +1 more source
Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis
Annals of Neurology, EarlyView.Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi +33 more
wiley +1 more source
Bullseye's representation of cerebral white matter hyperintensities
Journal of Neuroradiology, 2018 Visual rating scales have limited capacities to depict the regional distribution of cerebral white matter hyperintensities (WMH). We present a regional-zonal volumetric analysis alongside a visualization tool to compare and deconstruct visual rating scales.3D T1-weighted, T2-weighted spin-echo and FLAIR images were acquired on a 3T system, from 82 ...
Sudre, C. H. +13 more
openaire +6 more sources
Annals of Neurology, EarlyView.Objective The objective of this study was to examine whether machine learning has the capacity to prospectively identify and predict the emergence of Fragile X‐associated tremor/ataxia syndrome (FXTAS) among male fragile X premutation carriers (PCs). Methods We explored neuropsychological and motor evaluation metrics, brain magnetic resonance imaging ...
Chitrabhanu Gupta +10 more
wiley +1 more source
Multi-Scale Convolutional-Stack Aggregation for Robust White Matter Hyperintensities Segmentation [PDF]
, 2019 Segmentation of both large and small white matter hyperintensities/lesions in brain MR images is a challenging task which has drawn much attention in recent years.
Kirschke, Jan +4 more
core +3 more sources
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Annals of Neurology, EarlyView.Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Accurately predicting future hemorrhagic events in patients with cerebral amyloid angiopathy (CAA) remains a major clinical challenge. It is unknown whether cerebrospinal fluid (CSF) biomarkers of amyloid‐beta (Aβ) pathology are associated with increased hemorrhage risk in this population.
Philipp Arndt +15 more
wiley +1 more source
HeliyonImportance: Abnormal blood pressure pattern is an independent risk factor for vascular events. Blood pressure variability can predict cardiovascular and cerebrovascular disease outcomes and is closely associated with the risk of cognitive impairment ...
Bingqing Zhao +7 more
doaj +1 more source