Results 181 to 190 of about 24,272 (299)

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

Brain Pathology, EarlyView.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, Pedro González, Luis Jiménez‐Roldán, Guillermo García‐Posadas, Aurelio Hernández‐Laín, Ángel Pérez‐Núñez, Pilar Sánchez‐Gómez   +18 more
wiley   +1 more source

Associations of sleep behaviors with white matter hyperintensity volume in middle-aged to older adults. [PDF]

Alzheimers Dement
Ally M, Aslan DH, Sayre MK, Bharadwaj PK, Maltagliati S, Grilli MD, Lai MHC, Wilcox RR, Klimentidis YC, Raichlen DA, Alexander GE.   +10 more
europepmc   +1 more source

Dysregulated TIE‐2 expression is associated with blood‐brain barrier leakiness and Alzheimer's disease‐related neuropathology

Brain Pathology, EarlyView.
Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Carey Gleason, Barbara B. Bendlin, Ozioma Okonkwo, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson, Seth Love, J. Scott Miners   +12 more
wiley   +1 more source

Segmentasi White Matter Hyperintensity Pada Citra MRI Otak Menggunakan U-Net

Gray matter dan white matter adalah bagian pada otak yang memiliki fungsi yang sangat krusial dalam kerja otak. Gray matter adalah tempat di mana sel-sel saraf dan akson berada. Gray matter menempati mayoritas bagian cerebrum, cerebellum, dan batang otak.
Fahlevi, Muhammad Hashfi
core  

White matter hyperintensities and neurodegenerative dementias

Aging, 2019
openaire   +2 more sources

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

Brain Pathology, EarlyView.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle, Isabella Boesgaard, Austyn Roseborough, Meaghan Frank, Qi Zhang, Stephen H. Pasternak, Robert Hammond, Shawn N. Whitehead   +7 more
wiley   +1 more source

Severe Nonketotic Hyperglycinemia in Twins Caused by GLDC Variants: The Importance of Accurate Prenatal Variant Interpretation, Counseling, and VUS Disclosure

Prenatal Diagnosis, EarlyView.
Christopher Connolly, Brian Muchmore, Mallory Wagner, Zineb Ammous, Mohannad Ibrahim, Catherine E. Keegan, Elizabeth G. Ames   +6 more
wiley   +1 more source

Association of Long‐Term Trajectories in Obesity Indices With Neuroimaging Metrics and Cognition: A Population‐Based Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective Accurate assessment of gradual age‐related weight gain, a common phenomenon, is crucial for identifying brain health risks. This study investigated the associations between long‐term trajectories in obesity indices and brain structure and cognition. Methods This study included 1114 participants from the Kailuan cohort with ≥ 3 follow‐
Yanbo Liang, Zhiming Lu, Xiaoqing Yuan, Mingze Xu, Ying Hui, Shouling Wu, Zhenchang Wang, Ning Wu, Yuntao Wu, Han Lv   +9 more
wiley   +1 more source

Association of coronary artery calcium and carotid intima-media thickness with white matter hyperintensity. [PDF]

Medicine (Baltimore)
Shin S.
europepmc   +1 more source

Imaging and physiology across the high–low cerebrospinal fluid pressure spectrum: Navigating diagnostic uncertainty in headache practice

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study was conducted to provide a clinically oriented, mechanism‐based framework for interpreting neuroimaging across disorders of cerebrospinal fluid (CSF) pressure, with particular emphasis on patients who fall between classic diagnostic categories of spontaneous intracranial hypotension (SIH) and idiopathic intracranial ...
Andrew L. Callen, Kyle Jenkins
wiley   +1 more source