Results 221 to 230 of about 24,272 (299)

Midlife hypertension and late‐life cognition: weighting the LifeAfter90 study

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Midlife hypertension is a well‐established predictor of late‐life cognitive decline; however, few population‐representative estimates of this association exist among oldest‐old cohorts. METHODS LifeAfter90 (LA90) is an ethnoracially diverse cohort of individuals aged 90+ linked to midlife multiphasic health check‐ups (MHC).
Hilary L. Colbeth, Joseph N. Roscoe, Maria M. Corrada, Claire C. Meunier, Kristen M. George, M. Maria Glymour, Paola Gilsanz, Rachel A. Whitmer   +7 more
wiley   +1 more source

Cerebral small vessel disease and cognition in older adults across the neurodegenerative spectrum: insights from the COMPASS‐ND study

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Imaging‐based cerebral small vessel disease (CSVD) summary scores quantify CSVD burden. This study characterized CSVD scores and assessed their cognitive associations in older adults with various neurodegenerative diseases and cognitive profiles.
Dylan X. Guan, Zahinoor Ismail, Graham A. McLeod, Shahab Marzoughi, Eric E. Smith, Aravind Ganesh   +5 more
wiley   +1 more source

Prevalence and Risk Factors for Cerebral Microbleeds in Chinese Patients With Acute Ischemic Stroke

Brain and Behavior, Volume 16, Issue 6, June 2026.
Approximately half of the patients with AIS exhibited CMBs, particularly those classified under LAA and SVD subtypes. Hypertension and severe WMH were independently associated with CMB presence. Distinct clinical profiles were observed based on CMB burden and location.
Ruiming Zhu, Yinglin Yang, Xiaoyan Chen, Lei Hou, Xiangshu Cheng, Mianwang He   +5 more
wiley   +1 more source

Falls and Fear of Falling in Minor Stroke Patients With Vestibular Symptoms: A Longitudinal Observational Study

Brain and Behavior, Volume 16, Issue 6, June 2026.
This prospective study reveals that persistent vestibular symptoms, cerebral small vessel disease, and anxiety/depression predict long‐term fall risk in minor stroke patients. Early identification and intervention within the first 3 months poststroke may help mitigate balance impairment and improve outcomes.
Yao Zhong, Jiaokun Jia, Jiashu Li, Ruixuan Jiang, Xingquan Zhao, Yi Ju   +5 more
wiley   +1 more source

Mitigating disparities in diagnosis of dementia

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract The field of Alzheimer's disease and related dementias (AD/ADRD) is undergoing a transformative shift with a better understanding of disease biology, biomarker‐based diagnostics, and disease‐modifying therapies. Yet, these advancements risk exacerbating existing disparities in diagnosis and care.
Lycia Tramujas Vasconcellos Neumann, Simin Mahinrad, Erin Abner, Soo Borson, Goldie S. Byrd, Maria C. Carrillo, Lindsay Clark, Anthony N. Correro II, Kacie D. Deters, Peggye Dilworth‐Anderson, Rebecca M. Edelmayer, Jason D. Flatt, Crystal M. Glover, Joshua D. Grill, Carl V. Hill, Thomas K. Karikari, Fred B. Ketchum, Emily A. Largent, Jennifer H. Lingler, Jose A. Luchsinger, Gladys E. Maestre, Michelle M. Mielke, Sid O'Bryant, Ozioma C. Okonkwo, Monica W. Parker, Annalise M. Rahman‐Filipiak, Rema Raman, Suzanne E. Schindler, Jose Soria Lopez, Shana D. Stites, Astrid M. Suchy‐Dicey, Whitney Wharton, Rachel A. Whitmer, Lisa Ann Kirk Wiese, Charles C. Windon, Amy Kind, Lisa L. Barnes   +36 more
wiley   +1 more source

A Diagnostic Challenge: From Suspected Ischemic Stroke to Confirmed Herpetic Encephalitis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Multimodal neuroimaging in a case of HSV‐1 encephalitis mimicking malignant MCA stroke: from initial CT findings misinterpreted as large territorial infarction, through decompressive craniectomy for refractory intracranial hypertension, to MRI confirmation of non‐territorial haemorrhagic encephalitis prompting CSF analysis and acyclovir therapy ...
Mafalda Dias Neves, Miguel Gonçalves Pereira, Natacha Silveira, Susana Barbosa, José Maria Matos Sousa, Eduarda Pereira, Elisabete Monteiro   +6 more
wiley   +1 more source

Overcoming Cognitive Bias: A Case of Disseminated Neurocysticercosis in a Muslim Woman With Remote Pork Consumption

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Religious prohibitions against pork do not exclude individuals residing in endemic regions from contracting neurocysticercosis. Obtaining a detailed lifetime exposure history, including prior religious and dietary practices, is essential to overcome cognitive bias and prevent diagnostic delays.
Joseph Y. B. Nnang, Berjo Takoutsing, Astel Dongmo, Jeanne Annick Tsilla, Barah Mvuchiim, Roshina Numfor, Munteh Fang Nkwojei Randall, Elvira Aka, Ignatius Esene   +8 more
wiley   +1 more source

Understanding the Role of Genetic Testing in Diagnosing a Complex Pediatric Case

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Visualization of ZPR1 protein variants. ABSTRACT We report the case of a 13‐month‐old female with multiple congenital anomalies including microcephaly, generalized hypotonia, sensorineural hearing loss, visual impairment, alopecia, and hypoplastic kidneys with chronic kidney disease, and dysmorphic craniofacial features.
Giavanna Verdi, Aleksandra Foksinska, Elizabeth L. Nichols, Erinn O. Schmit, Andrew Watson, Madeline Eckenrode, Nathaniel H. Robin   +6 more
wiley   +1 more source

Acute Disseminated Encephalomyelitis Presenting as Fever of Unknown Origin in a 4‐Year‐Old Boy: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT A 4‐year‐old boy presented with prolonged fever of unknown origin and systemic inflammation without early neurological signs. MRI revealed multifocal demyelination, and MOG antibodies were positive. He was diagnosed with ADEM and treated with steroids and IVIg, but relapsed twice, consistent with multiphasic disseminated encephalomyelitis ...
Pedro Pau
wiley   +1 more source