Results 231 to 240 of about 24,272 (299)

Recurrent Acute Limb Ischaemia due to Malignant Thromboembolism Involving Bilateral Lower Limbs Simultaneously

open access: yesCancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Acute Limb Ischaemia (ALI) is a limb and life‐threatening condition that is often associated with cardiovascular disease, atrial fibrillation (AF), diabetes and smoking. It is less commonly associated with active malignancy. There is growing evidence regarding this association.
Amos Au, Audrey Choy, Ming Yii
wiley   +1 more source

Methionine, Homocysteine, and Methylation Levels Predict Cognitive Decline in Alzheimer's Disease

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Elevated homocysteine and reduced methionine/methylation levels predict accelerated cognitive decline and white matter damage over one year in AD patients. This metabolic imbalance reveals a modifiable pathway linked to vitamin B12 deficiency. Targeting one‐carbon metabolism may provide novel therapeutic strategies to delay neurodegeneration.
Xiaoyu Zhang   +8 more
wiley   +1 more source

The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion‐Tensor‐Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 6, Page 1509-1545, June 2026.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca   +3 more
wiley   +1 more source

FMRI Approaches to Mapping Cerebrovascular Reactivity: Comparison of Gradient Echo BOLD and Spin Echo BOLD With Arterial Spin Labeling

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 6, Page 3309-3321, June 2026.
ABSTRACT Purpose To compare markers of cerebrovascular reactivity (CVR) measured with Gradient Echo (GE, T2*w) and Spin‐Echo (SE, T2w) BOLD fMRI with quantitative physiological CVR measured using ASL. Methods CVR, the ability of blood vessels to dilate and increase cerebral blood flow (CBF), can be investigated with ASL fMRI but has a low signal‐to ...
Sara Pomante   +13 more
wiley   +1 more source

White matter hyperintensity burden predicts domain-specific cognitive decline across the Alzheimer's disease continuum. [PDF]

open access: yesSci Rep
Nasiri H   +15 more
europepmc   +1 more source

Hierarchical Bayesian Modelling Improves Microstructural Parameter Mapping in Diffusion and Exchange MRI Data

open access: yesNMR in Biomedicine, Volume 39, Issue 6, June 2026.
Our hierarchical Bayesian modelling (HBM) technique is demonstrated in two neuroimaging diffusion MRI models. When compared with least‐squares (LSQ) minimisation, HBM increased the accuracy, precision, contrast‐to‐noise ratio and parameter map quality in simulated and human data. HBM also resolved local parameter variations associated with white matter
Elizabeth Powell   +5 more
wiley   +1 more source

Impact of regional white matter hyperintensity patterns on cognitive trajectories in NACC. [PDF]

open access: yesAlzheimers Dement
Rotblatt LJ   +5 more
europepmc   +1 more source

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