Results 231 to 240 of about 24,272 (299)
ABSTRACT Background Acute Limb Ischaemia (ALI) is a limb and life‐threatening condition that is often associated with cardiovascular disease, atrial fibrillation (AF), diabetes and smoking. It is less commonly associated with active malignancy. There is growing evidence regarding this association.
Amos Au, Audrey Choy, Ming Yii
wiley +1 more source
Methionine, Homocysteine, and Methylation Levels Predict Cognitive Decline in Alzheimer's Disease
Elevated homocysteine and reduced methionine/methylation levels predict accelerated cognitive decline and white matter damage over one year in AD patients. This metabolic imbalance reveals a modifiable pathway linked to vitamin B12 deficiency. Targeting one‐carbon metabolism may provide novel therapeutic strategies to delay neurodegeneration.
Xiaoyu Zhang +8 more
wiley +1 more source
Association between carotid atherosclerotic plaque characteristics and white matter hyperintensity in cerebral small vessel disease. [PDF]
Feng Q, Wang T, Zhu L.
europepmc +1 more source
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca +3 more
wiley +1 more source
ABSTRACT Purpose To compare markers of cerebrovascular reactivity (CVR) measured with Gradient Echo (GE, T2*w) and Spin‐Echo (SE, T2w) BOLD fMRI with quantitative physiological CVR measured using ASL. Methods CVR, the ability of blood vessels to dilate and increase cerebral blood flow (CBF), can be investigated with ASL fMRI but has a low signal‐to ...
Sara Pomante +13 more
wiley +1 more source
White matter hyperintensity burden predicts domain-specific cognitive decline across the Alzheimer's disease continuum. [PDF]
Nasiri H +15 more
europepmc +1 more source
Our hierarchical Bayesian modelling (HBM) technique is demonstrated in two neuroimaging diffusion MRI models. When compared with least‐squares (LSQ) minimisation, HBM increased the accuracy, precision, contrast‐to‐noise ratio and parameter map quality in simulated and human data. HBM also resolved local parameter variations associated with white matter
Elizabeth Powell +5 more
wiley +1 more source
Impact of regional white matter hyperintensity patterns on cognitive trajectories in NACC. [PDF]
Rotblatt LJ +5 more
europepmc +1 more source

