Results 31 to 40 of about 197,800 (388)

New insights in addressing cerebral small vessel disease: Associated with extracellular fluid in white matter

Frontiers in Neuroscience, 2022
ObjectiveTo explore the role of extracellular fluid, assessed by diffusion tensor imaging (DTI) metrics of free water (FW), in the white matter of patients with cerebral small vessel disease (CSVD).Materials and methodsThe baseline clinical and imaging ...
Haiyuan Lan, Xinjun Lei, Zhihua Xu, Songkuan Chen, Wanfeng Gong, Yunqi Cai   +5 more
doaj   +1 more source

Diabetes mellitus and white matter hyperintensity [PDF]

Geriatrics & Gerontology International, 2015
White matter hyperintensity (WMH) is a brain lesion detected as a high‐intensity area in magnetic resonance imaging T2 and fluid‐attenuated inversion recovery images, and it has been suggested that WMH reflects damage to small vessels in periventricular and subcortical areas. Although WMH has been linked to the incidence of stroke, more recently it has
Yoshiaki, Tamura, Atsushi, Araki
openaire   +2 more sources

Prevalence of Isolated Nocturnal Hypertension and Development of Arterial Stiffness, Left Ventricular Hypertrophy, and Silent Cerebrovascular Lesions: The KoGES (Korean Genome and Epidemiology Study)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Apart from nondippers’ impact on cardiovascular events, the prevalence of isolated nocturnal hypertension (INH) and its consequences on both the heart and brain were not clearly investigated in the general population.
Seong Hwan Kim, Chol Shin, Sunwon Kim, Jin‐Seok Kim, Sang Yup Lim, Hyeong‐Seok Seo, Hong Euy Lim, Ki‐Chul Sung, Goo‐Yeong Cho, Seung Ku Lee, Yong‐Hyun Kim   +10 more
doaj   +1 more source

White matter hyperintensity distribution differences in aging and neurodegenerative disease cohorts

bioRxiv, 2021
Introduction White matter hyperintensities (WMHs) are common magnetic resonance imaging (MRI) findings in the aging population in general, as well as in patients with neurodegenerative diseases.
M. Dadar, S. Mahmoud, M. Zhernovaia, R. Camicioli, J. Maranzano, S. Duchesne   +5 more
semanticscholar   +1 more source

Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients. [PDF]

PLoS ONE, 2015
Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether ...
Caroline M J Loos, Pim Klarenbeek, Robert J van Oostenbrugge, Julie Staals   +3 more
doaj   +1 more source

Independent and additive contribution of white matter hyperintensities and Alzheimer’s disease pathology to basal forebrain cholinergic system degeneration

NeuroImage: Clinical, 2023
Objectives: Degeneration of the cholinergic basal forebrain nuclei (CBFN) system has been studied extensively in Alzheimer's disease (AD). White matter hyperintensities are a hallmark of aging as well as a common co-morbidity of AD, but their ...
Christine Kindler, Neeraj Upadhyay, Zeynep Bendella, Franziska Dorn, Vera C. Keil, Gabor C. Petzold   +5 more
doaj   +1 more source

White Matter Hyperintensities and Medication Adherence [PDF]

Biological Research For Nursing, 2008
White matter hyperintensities (WMH) are associated with hypertension, age, and cognitive function, but the association between WMH and medication adherence has not been examined. The intent of this investigation was to consider the potential implications of hypertension-related brain morphological changes on medication adherence and thereby improve ...
Kathleen C, Insel, Sheryl L, Reminger, Chao-Pin, Hsiao   +2 more
openaire   +2 more sources

White matter hyperintensities and hypobaric exposure [PDF]

Annals of Neurology, 2014
ObjectiveDemonstrate that occupational exposure to nonhypoxic hypobaria is associated with subcortical white matter hyperintensities (WMHs) on fluid‐attenuated inversion recovery magnetic resonance imaging (MRI).MethodsEighty‐three altitude chamber personnel (PHY), 105 U‐2 pilots (U2P), and 148 age‐ controlled and health‐matched doctorate degree ...
Stephen A, McGuire, Paul M, Sherman, S Andrea, Wijtenburg, Laura M, Rowland, Patrick M, Grogan, John H, Sladky, Andrew Y, Robinson, Peter V, Kochunov   +7 more
openaire   +2 more sources

Correlations among peripheral blood markers, white matter hyperintensity, and cognitive function in patients with non-disabling ischemic cerebrovascular events

Frontiers in Aging Neuroscience, 2022
BackgroundBoth inflammation and cerebral white matter injury are closely associated with vascular cognitive impairment (VCI). The aim of this study was to analyze the correlation between peripheral serological markers, white matter injury, and cognitive ...
Binghan Li, Bingying Du, Zhengsheng Gu, Chenghao Wu, Yuhao Tan, Chenrui Song, Yawen Xu, Ge Yin, Xin Gao, Weisen Wang, Xu Sun, Xiaoying Bi   +11 more
doaj   +1 more source

Longitudinal patterns of leukoaraiosis and brain atrophy in symptomatic small vessel disease. [PDF]

, 2016
Cerebral small vessel disease is a common condition associated with lacunar stroke, cognitive impairment and significant functional morbidity. White matter hyperintensities and brain atrophy, seen on magnetic resonance imaging, are correlated with ...
Andrew J. Lawrence, Ashburner, Christian Lambert, Curnes, Eva Zeestraten, Hugh S. Markus, Kraha, Philip Benjamin, Thomas R. Barrick, Wender   +9 more
core   +1 more source