Results 51 to 60 of about 197,800 (388)

Relationship Between Type 2 Diabetes and White Matter Hyperintensity: A Systematic Review

Frontiers in Endocrinology, 2020
White matter (WM) disease is recognized as an important cause of cognitive decline and dementia. White matter lesions (WMLs) appear as white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI) scans of the brain.
Dan-Qiong Wang, Lei Wang, Miaomiao Wei, Xiao-shuang Xia, Xiaolin Tian, X. Cui, Xin Li   +6 more
semanticscholar   +1 more source

A Postmortem MRI Study of Cerebrovascular Disease and Iron Content at End-Stage of Fragile X-Associated Tremor/Ataxia Syndrome

Cells, 2023
Brain changes at the end-stage of fragile X-associated tremor/ataxia syndrome (FXTAS) are largely unknown due to mobility impairment. We conducted a postmortem MRI study of FXTAS to quantify cerebrovascular disease, brain atrophy and iron content, and ...
Jun Yi Wang, Gerard J. Sonico, Maria Jimena Salcedo-Arellano, Randi J. Hagerman, Veronica Martinez-Cerdeno   +4 more
doaj   +1 more source

Resting state connectivity and cognitive performance in adults with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy [PDF]

, 2016
Cognitive impairment is an inevitable feature of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), affecting executive function, attention and processing speed from an early stage.
Cullen, Breda, Kalladka, Dheeraj, Krishnadas, Rajeev, López-González, Maria R., Moreton, Fiona C., Muir, Keith W., Santosh, Celestine, Schwarzbauer, Christian, Stringer, Michael S.   +8 more
core   +1 more source

Brain amyloid and vascular risk are related to distinct white matter hyperintensity patterns

Journal of Cerebral Blood Flow and Metabolism, 2020
White matter hyperintensities (WMHs) are associated with vascular risk and Alzheimer’s disease. In this study, we examined relations between WMH load and distribution, amyloid pathology and vascular risk in 339 controls and cases with either subjective ...
L. Pålhaugen, C. Sudre, Sandra Tecelão, A. Nakling, I. S. Almdahl, L. Kalheim, M. Cardoso, Stein H Johnsen, A. Rongve, D. Aarsland, A. Bjørnerud, P. Selnes, T. Fladby   +12 more
semanticscholar   +1 more source

Menopausal hot flashes and white matter hyperintensities [PDF]

Menopause, 2016
Hot flashes are classic symptoms of menopause. Emerging data link hot flashes to cardiovascular disease (CVD) risk, yet whether hot flashes are related to brain health is poorly understood. We examined the relationship between hot flashes (measured via physiologic monitor and self-report) and white matter hyperintensities (WMH) among midlife women ...
Rebecca C, Thurston, Howard J, Aizenstein, Carol A, Derby, Ervin, Sejdić, Pauline M, Maki   +4 more
openaire   +2 more sources

Semisupervised white matter hyperintensities segmentation on MRI

Human Brain Mapping, 2022
AbstractThis study proposed a semisupervised loss function named level‐set loss (LSLoss) for cerebral white matter hyperintensities (WMHs) segmentation on fluid‐attenuated inversion recovery images. The training procedure did not require manually labeled WMH masks.
Fan Huang, Peng Xia, Varut Vardhanabhuti, Sai‐Kam Hui, Kui‐Kai Lau, Henry Ka‐Fung Mak, Peng Cao   +6 more
openaire   +2 more sources

A comparison of location of acute symptomatic vs. 'silent' small vessel lesions [PDF]

, 2015
Background: Acute lacunar ischaemic stroke, white matter hyperintensities, and lacunes are all features of cerebral small vessel disease. It is unclear why some small vessel disease lesions present with acute stroke symptoms, whereas others typically do ...
Bailey EL, Bamford J, Chowdhury D, Clayden JD, De Maesschalck R, Del Bene A, Fisher CM, Fukui T, Haley AP, Jackson CA, Kimberly WT, Longstreth WT, Loos CM, Moreau F, O'Sullivan M, Oishi K, Potter GM, Rost NS, Sacco S, Saini M, Valdes Hernandez M, Valdes Hernandez MC, Viswanathan A, Wardlaw JM, Wardlaw JM, Wardlaw JM, Wardlaw JM, Wen W, Wright CB   +28 more
core   +2 more sources

Associations between arterial stiffness, depressive symptoms and cerebral small vessel disease: cross-sectional findings from the AGES-Reykjavik Study. [PDF]

, 2015
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Garcia, Melissa E, Gudnason, Vilmundur, Harris, Tamara B, Henry, Ronald M A, Jonsson, Palmi V, Launer, Lenore J, Levey, Andrew S, Mitchell, Gary F, Sigurdsson, Sigurdur, Stehouwer, Coen D A, van Buchem, Mark A, van Sloten, Thomas T   +11 more
core   +1 more source

Periventricular White Matter Hyperintensities and Functional Decline [PDF]

Journal of the American Geriatrics Society, 2017
Background/Objectives We previously showed that global brain white matter hyperintensity volume ( WMHV ) was associated with accelerated long‐term functional decline. The objective of the current study was to determine whether
Mandip S, Dhamoon, Ying-Kuen, Cheung, Ahmet, Bagci, Noam, Alperin, Ralph L, Sacco, Mitchell S V, Elkind, Clinton B, Wright   +6 more
openaire   +2 more sources

Imaging of Angiogenesis in White Matter Hyperintensities

Journal of the American Heart Association, 2023
Background White matter hyperintensities (WMHs) are areas of increased signal intensity on T2‐weighted magnetic resonance imaging (MRI). WMH penumbra may be a potential target for early intervention in WMHs. We explored the relationship between angiogenesis and WMH penumbra in patients with WMHs.
Lingling Ding, Bo Hou, Jie Zang, Tong Su, Feng Feng, Zhaohui Zhu, Bin Peng   +6 more
openaire   +3 more sources