Results 71 to 80 of about 197,800 (388)

Microstructural white matter changes preceding white matter hyperintensities in migraine

Neurology, 2019
We used magnetization transfer imaging to assess white matter tissue integrity in migraine, to explore whether white matter microstructure was more diffusely affected beyond visible white matter hyperintensities (WMHs), and to explore whether focal invisible microstructural changes precede visible focal WMHs in migraineurs.We included 137 migraineurs ...
Arkink, E.B., Palm-Meinders, I.H., Koppen, H., Milles, J., Lew, B. van, Launer, L.J., Hofman, P.A.M., Terwindt, G.M., Buchem, M.A. van, Ferrari, M.D., Kruit, M.C.   +10 more
openaire   +5 more sources

Migraine and white matter hyperintensities [PDF]

Neurology, 2013
OBJECTIVE: Migraine is associated with white matter hyperintensities (WMH) cross-sectionally, but its effect on WMH progression is uncertain. METHODS: Participants in the Atherosclerosis Risk in Communities cohort study (n = 10,924) completed a standardized headache questionnaire between 1993 and 1995.
Ali G, Hamedani, Kathryn M, Rose, B Lee, Peterlin, Thomas H, Mosley, Laura H, Coker, Clifford R, Jack, David S, Knopman, Alvaro, Alonso, Rebecca F, Gottesman   +8 more
openaire   +2 more sources

Exploration of heterogeneity in risk factors associated with imaging subtypes of white matter hyperintensities on fluid-attenuated inversion recovery magnetic resonance imaging

Frontiers in Neurology
BackgroundWhite matter hyperintensity (WMH), a critical early biomarker in cerebrovascular/neurodegenerative diseases, has traditionally been studied via global volume or subjective scoring, which overlooks its spatial heterogeneity, leading to ...
Yonglong Li, Xiufu Zhang, Haotian Wang, Linrong Jiang, Zhaoyang Gu, Jun Zhou, Ruipeng Liang   +6 more
doaj   +1 more source

A Fully Automated Visual Grading System for White Matter Hyperintensities of T2-Fluid Attenuated Inversion Recovery Magnetic Resonance Imaging

Journal of Integrative Neuroscience, 2023
Background: The Fazekas scale is one of the most commonly used visual grading systems for white matter hyperintensity (WMH) for brain disorders like dementia from T2-fluid attenuated inversion recovery magnetic resonance (MR) images (T2-FLAIRs). However,
ZunHyan Rieu, Regina EY Kim, Minho Lee, Hye Weon Kim, Donghyeon Kim, JeongHyun Yong, JiMin Kim, MinKyoung Lee, Hyunkook Lim, JeeYoung Kim   +9 more
doaj   +1 more source

Pulse Pressure, White Matter Hyperintensities, and Cognition: Mediating Effects Across the Adult Lifespan

Annals of Clinical and Translational Neurology
Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition.
Jade Hannan, Sarah Newman‐Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman‐Norlund, Chris Rorden, Julius Fridriksson, Leonardo Bonilha, Nicholas Riccardi   +8 more
doaj   +1 more source

Necrotizing meningoencephalitis in atypical dog breeds: a case series and literature review. [PDF]

, 2014
BackgroundCanine necrotizing meningoencephalitis (NME) is a fatal, noninfectious inflammatory disease of unknown etiology. NME has been reported only in a small number of dog breeds, which has led to the presumption that it is a breed-restricted disorder.
Cooper, JJ, Levine, JM, Porter, BF, Schatzberg, SJ, Siso, S, Summers, BA, Vernau, KM, Young, BD   +7 more
core   +1 more source

Blood pressure, glycemic control, and white matter hyperintensity progression in type 2 diabetics

Neurology, 2019
Objective To determine whether higher blood pressure mean (BPM) or hemoglobin A1c is associated with progression of white matter hyperintensity (WMH) on MRI in patients with type 2 diabetes, and whether intensive blood pressure or glycemic control can ...
A. D. de Havenon, J. Majersik, D. Tirschwell, J. S. McNally, G. Stoddard, Natalia S. Rost   +5 more
semanticscholar   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

White matter hyperintensity, neurofilament light chain, and cognitive decline

Annals of Clinical and Translational Neurology, 2023
Objective We aimed to determine whether combining white matter hyperintensity (WMH) with neurofilament light chain (NfL) could provide additional information for cognition in older adults.
Anisa Dhana, Charles DeCarli, Klodian Dhana, Pankaja Desai, Robert S. Wilson, Denis A. Evans, Kumar B. Rajan   +6 more
doaj   +1 more source

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy [PDF]

, 2006
Background: Progressive multifocal leukoencephalopathy (PML) was reported to have developed in three patients treated with natalizumab. We conducted an evaluation to determine whether PML had developed in any other treated patients.
Barkhof, F., Clifford, D.B., Curfman, B., Fahle, G., Fischer, S., Habil, M., Hou, J., Jäger, H.R., Major, E.O., Miszkiel, K., Mueller-Lenke, N., Radue, E.-W., Ryschkewitsch, C., Sanchez, E., Yousry, T.A.   +14 more
core   +1 more source