Results 71 to 80 of about 143,855 (296)

Plasma vitamin B-12 status and cerebral white-matter lesions [PDF]

, 2009
Background and objective: Elevated homocysteine has been associated with a higher prevalence of cerebral white-matter lesions and infarcts, and worse cognitive performance.
Refsum, H, Smith, AD, Breteler, Monique, Lau, Lonneke, Johnston, C   +4 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Migraine or any headaches and white matter hyperintensities and their progression in women and men

The Journal of Headache and Pain
Background Cross-sectional and longitudinal studies have been conducted to investigate the association between migraine and any headache and white matter hyperintensities (WMH).
Sara Helena Schramm, I. Tenhagen, M. Jokisch, J. Gronewold, S. Moebus, S. Caspers, Z. Katsarava, R. Erbel, A. Stang, B. Schmidt   +9 more
doaj   +1 more source

Systemic oxidative stress and cognitive function in Parkinson’s disease with different PWMH or DWMH lesions

BMC Neurology, 2021
Background Parkinson’s disease (PD), frequently accompanied by cognitive impairments, is associated with systemic oxidative stress and abnormal structural changes on brain images. We aimed to identify the correlation between systemic oxidative stress and
Ta-Chih Chang, Yi-Cun Chen, Yu-Chi Huang, Wei-Che Lin, Cheng-Hsien Lu   +4 more
doaj   +1 more source

Segmentation of white matter lesions from volumetric MR images. [PDF]

, 1999
Quantitative analysis of the changes to the brain’s white matter is an important objective for a better understanding of pathological changes in various forms of degenerative brain diseases. To achieve an accurate quantification, an algorithm is proposed
Hojjatoleslami, Ali, S. A. Hojjatoleslami, D. Y. von Cramon, Kruggel, F., Hojjatoleslami, S. A., von Cramon, D. Yves, Hojjatoleslami, S., von Cramon, D., F. Kruggel   +8 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Exploring the Link between Hypertension and Cerebral White Matter Changes in Chronic Kidney Disease

Kidney & Blood Pressure Research
Background: Patients diagnosed with chronic kidney disease (CKD) are at a higher risk of encephalopathy, a condition exacerbated by the presence of various chronic diseases.
Kung-Chao Chen, Feng-Ching Shen, Wen-Ching Chen, Hsiu-Fen Lin, Teng-Hui Huang, Ming-Yen Lin, Shu-Li Wang, Fan-Pei Gloria Yang, Mei-Chuan Kuo, Yi-Wen Chiu, Shang-Jyh Hwang, Ping-Hsun Wu, Yi-Ting Lin   +12 more
doaj   +1 more source

White matter lesions and intra-arterial thrombolysis [PDF]

, 2018
The aim of the study was to assess the influence of white matter lesions in patients with acute ischemic stroke treated with intra-arterial thrombolysis (IAT). From September 2003 to January 2010, we treated 400 patients with IAT at our institution.
Galimanis, Aekaterini, Arnold, Marcel, Jung, Simon, Ballinari, Pietro, Mono, Marie, Fischer, Urs, Gralla, Jan, Mattle, Heinrich, Schroth, Gerhard, Brekenfeld, Caspar, Weck, Anja, El-Koussy, Marwan, Findling, Oliver, De Marchis, Gian   +13 more
core  

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Asymptomatic Brain Lesions on Cranial Magnetic Resonance Imaging in Inflammatory Bowel Disease

Gut and Liver, 2013
Background/AimsThis study aimed to examine the frequency and type of asymptomatic neurological involvement in inflammatory bowel disease (IBD) using cranial magnetic resonance imaging (MRI).Methods : Fifty-one IBD patients with no known neurological ...
doaj   +1 more source