Results 91 to 100 of about 260,120 (295)

Effects of prenatal alcohol exposure on the development of white matter volume and change in executive function

NeuroImage: Clinical, 2014
Prenatal alcohol exposure can cause a wide range of deficits in executive function that persist throughout life, but little is known about how changes in brain structure relate to cognition in affected individuals. In the current study, we predicted that
P. Gautam, S.C. Nuñez, K.L. Narr, E.C. Kan, E.R. Sowell   +4 more
doaj   +1 more source

Genetic Variation in White Matter Hyperintensity Volume in the Framingham Study [PDF]

Stroke, 2004
Background and Purpose— In a previous study of normal elderly male twins, the heritability of quantitative white matter hyperintensity (WMH) volume has been estimated to be high (0.73). We investigated heritability of WMH in a family-based sample of the Framingham Heart Study for sex differences and ...
Larry D, Atwood, Philip A, Wolf, Nancy L, Heard-Costa, Joseph M, Massaro, Alexa, Beiser, Ralph B, D'Agostino, Charles, DeCarli   +6 more
openaire   +2 more sources

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Brain structural alterations correlate with motor dysfunction in children with spastic cerebral palsy: a quantitative MRI study

European Journal of Medical Research
Background Spastic cerebral palsy (CP) is a common cause of motor disability in children which caused by non-progressive brain injury. This study aimed to investigate the correlation between quantitative brain MRI parameters and motor dysfunction in ...
Qiang Wang, Jiale Zhang, Xiang Ren, Qijia Zhan, Wenbin Jiang   +4 more
doaj   +1 more source

White Matter Hyperintensity Volume and Cerebral Perfusion in Older Individuals with Hypertension Using Arterial Spin-Labeling

, 2016
BACKGROUND AND PURPOSE: White matter hyperintensities of presumed vascular origin in elderly patients with hypertension may be part of a general cerebral perfusion deficit, involving not only the white matter hyperintensities but also the surrounding ...
Caan, M. W. A., van Dalen, J. W., Steenwijk, M. D., Richard, E., Mutsaerts, H. J. M. M., Vrenken, H., van Gool, W. A., Majoie, C. B. L. M., Nederveen, A. J.   +8 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

A voxel-based morphometric study of age- and sex-related changes in white matter volume in the normal aging brain

Neuropsychiatric Disease and Treatment, 2016
Haijing Liu*, Lixin Wang*, Zuojun Geng, Qingfeng Zhu, Zhenhu Song, Ruiting Chang, Huandi Lv Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China *These authors contributed equally to ...
Liu H, Wang L, Geng Z, Zhu Q, Song Z, Chang R, Lv H   +6 more
doaj  

Apnea-hypopnea index, nocturnal arousals, oxygen desaturation and structural brain changes: A population-based study

Neurobiology of Sleep and Circadian Rhythms, 2016
Sleep apnea has been related to brain changes such as atrophy. However, which component of sleep apnea, the apnea-hypopnea index (AHI), nocturnal oxygen desaturation or arousals, can explain this association is unclear.
Lisette A. Zuurbier, Meike W. Vernooij, Annemarie I. Luik, Desana Kocevska, Albert Hofman, Harry Whitmore, M. Arfan Ikram, Henning Tiemeier   +7 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

The dyslexia candidate locus on 2p12 is associated with general cognitive ability and white matter structure

, 2012
Independent studies have shown that candidate genes for dyslexia and specific language impairment (SLI) impact upon reading/language-specific traits in the general population.
Newbury, Dianne F, Dianne F Newbury, Dianne F. Newbury, Morris, Andrew P., Pennell, CE, Morris, Andrew P, Monaco, Anthony P, Anthony P. Monaco, Susan Ring, Ring, Susan, Whitehouse, Andrew J.O., Scerri, TS, Juha Kere, Ring Susan, Joel B Talcott, Fahimeh Darki, Hans Matsson, Pennell, Craig E, Whitehouse Andrew J. O., Morris Andrew P., Talcott, JB, Talcott Joel B., Torkel Klingberg, Kere Juha, Kere, Juha, Whitehouse, Andrew J O, Darki, Fahimeh, Monaco, AP, Stein, J, Ring, S, Myriam Peyrard, Joel B. Talcott, Silvia Paracchini, Craig E. Pennell, Qi W Ang, Thomas S. Scerri, Anthony P Monaco, Matsson Hans, Thomas S Scerri, Newbury Dianne F., Stein, John, Andrew P Morris, Ang Qi W., Ang, QW, Monaco, Anthony P., Paracchini, Silvia, Peyrard-Janvid, M, Myriam Peyrard-Janvid, Pennell Craig E., Klingberg, Torkel, John Stein, Ang, Qi W., Kere, J, Scerri Thomas S., Scerri, Thomas S, Pennell, Craig E., Talcott, Joel B., Matsson, Hans, Whitehouse, AJ, Craig E Pennell, Talcott, Joel B, Klingberg Torkel, Morris, Andrew, Peyrard-Janvid, Myriam, Whitehouse, Andrew J. O., Talcott, Joel, Monaco Anthony P., Ang, Qi W, Klingberg, T, Darki Fahimeh, Peyrard-Janvid Myriam, Paracchini, S, Morris, AP, Andrew P. Morris, Qi W. Ang, Stein John, Andrew J. O. Whitehouse, Matsson, H, Andrew J O Whitehouse, Newbury, Dianne F., Darki, F, Newbury, DF, Paracchini Silvia, Thomas S. Scerri, Scerri, Thomas S.   +84 more
core   +1 more source