Results 111 to 120 of about 3,975,496 (251)

Influence of 6‐Trifluoromethyluracil Versus Chloride Counterions in the Properties of Bis‐(1,10‐Phenanthroline)chloridecopper(II) Motif: Spectroscopic and In Vitro Biological Activity Assays

European Journal of Inorganic Chemistry, EarlyView.
This work explores the influence of 6‐trifluoromethyluracil versus chloride counterions on the antibacterial and antitumoral activities of bis‐(1,10‐phenanthroline)chloridecopper(II) motif. The counterion modulates antibacterial potency and the identity of the dominant reactive species, while leaving DNA recognition by the shared cation essentially ...
Francisco Mastrobuono‐Cordeiro, Gabriele de M. Pereira, Douglas H. Nakahata, Stefano Scoditti, Fernanda V. P. de V. Azevedo, Letícia P. de Oliveira, Silmara C. L. Frajácomo, Javier Ellena, Pedro H. de O. Santiago, Daniel Reta, Gilberto C. Franchi, Wilton R. Lustri, Carmen S. P. Lima, Pedro P. Corbi, Raphael E. F. de Paiva   +14 more
wiley   +1 more source

Immunotherapy for Head and Neck Cutaneous Squamous Cell Carcinoma with Perineural Spread: A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Background Immunotherapy is increasingly used for head and neck cutaneous squamous cell carcinoma (cSCC) with perineural spread (PNS), though outcomes remain poorly defined. Methods A systematic review was conducted according to PRISMA and MOOSE guidelines.
Jai Paris, James Tsimiklis, Ayushi Agarwal, Jessica Y. Tong, Dinesh Selva   +4 more
wiley   +1 more source

Prevention of Work‐Related Musculoskeletal Disorders and Career Sustainability in Head and Neck Reconstructive Surgery: Integrating Ergonomics and Physical Conditioning

Head &Neck, EarlyView.
ABSTRACT Background Head and neck reconstructive and plastic surgery exposes surgeons to prolonged static posture, sustained visualization of a narrow operative field, cervical and shoulder loading, fine‐motor work, and extended standing. These demands create a substantial occupational musculoskeletal burden.
Babak Shadgan, Oleksandr Butskiy, Nikos C. Apostolopoulos, Lernik Sarkissian, Brent Chang, Donald Anderson   +5 more
wiley   +1 more source

Conhecimento actual sobre complicações major após irradiação cerebral total ou radiocirurgia.

Acta Médica Portuguesa, 2010
Brain radiotherapy aims at controlling the pathological lesion(s) as well as avoiding damaging critical structures. However, side effects may occur. Neurocognitive function is often involved impairing quality of life.
Fátima Amaral
doaj   +1 more source

Combination of vorinostat with whole-brain radiotherapy in the treatment of brain metastases.

Journal of Clinical Oncology, 2010
TPS181 Background: A third of patients with solid malignancies develop brain metastases. Expected overall survival is 4-7 months depending on age, performance status, and extracranial disease.
Y. Lawrence, R. Pfeffer, Maria Werner-Wasik, H. Choy, Adam Dicker   +4 more
openaire   +2 more sources

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Whole-liver radiotherapy for diffuse liver metastases improves liver enzymes and related factors

, 2019
Whole-liver radiotherapy for diffuse liver metastases improves liver enzymes and related ...
Katsuyuki Karasawa (6181457), Keiji Nihei (6181454), Yosuke Osawa (582754), Takuya Shimizuguchi (6181448), Hiroaki Ogawa (6181451), Kei Ito (151948)   +5 more
core   +1 more source

Descriptive Analysis of Epidemiology, Demographic Characteristics, and Survival of Dedifferentiated Liposarcoma in France

International Journal of Cancer, EarlyView.
ABSTRACT Dedifferentiated liposarcoma (DDLPS) is a rare soft tissue sarcoma with limited real‐world epidemiologic data. This nationwide retrospective study describes the epidemiology, management, and outcomes of DDLPS in France using the NETSARC+ national sarcoma registry.
Julien Bollard, Nicolas Penel, Thibaud Valentin, Robin Tranchant, Marie Najean, Christophe Maritaz, Maud Toulmonde, Matthieu Faron, Axel Le Cesne, Florence Duffaud, Alice Hervieu, Nelly Firmin, Emmanuelle Bompas, Sixtine De Percin, Christophe Perrin, Pascale Dubray‐Longeras, Thomas Ryckewaert, Françoise Ducimetiere, Claire Chemin, Christophe Bouvier, Magali Morelle, Jean‐Yves Blay, Mehdi Brahmi, Sarah Watson   +23 more
wiley   +1 more source

Brain Atrophy and Leukoencephalopathy Following Tarlatamab: Case Report

Respirology Case Reports
We describe the case of a 74‐year‐old female diagnosed with extensive‐stage small cell lung cancer. Initially, she received carboplatin, etoposide and atezolizumab, followed by amrubicin as second‐line treatment and nogitecan as third‐line treatment ...
Kiriko Onishi, Toki Kitano, Yusuke Fujioka, Moeko Ota, Fumie Onishi, Kohei Miyake, Hisaaki Tanaka, Nobukazu Fujimoto   +7 more
doaj   +1 more source

Brain metastasis from urachal carcinoma: the importance of locally aggressive treatment

Rare Tumors, 2012
We present the case of a 52 years old woman who developed multiple brain metastasis after cystectomy with anterior exenteration and chemotherapy. She received whole-brain radiotherapy with 20 gray in 5 sessions.
Daniel Taussky, Pierre I. Karakiewicz, Mathieu Latour, Normand Blais   +3 more
doaj   +1 more source