Results 131 to 140 of about 3,975,496 (251)

Radiation-induced Optic Neuropathy following Whole-Brain Radiotherapy

, 2017
Radiation-induced optic neuropathy (RION) is a rare complication of radiotherapy to the anterior visual pathway (AVP) which results in irreversible vision loss. Experimental data support a dose tolerance for the AVP of 50 Gy.
Ian Ferguson; Leah Levi; Gregory Van Stavern
core  

Comparison of Continuous‐Time Random Walk and Fractional Order Calculus Diffusion Models for Preoperative Breast Lesion Characterization: Diagnosis, Biomarker Prediction and Molecular Subtyping

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Accurate preoperative characterization of breast lesions is important for individualized management. The conventional monoexponential (Mono) model has limited ability to capture the complex microstructure of lesions. Non‐Gaussian diffusion models, including continuous‐time random walk (CTRW) and fractional‐order calculus (FROC), may
Yimeng Cao, Shaomin Li, Zhexuan Yang, Xueyan Liu, Shifang Tan, Tian Ren, Wenjia Wang, Haiyang Li, Xingzhi Chen, Xin Zhao, Meiying Cheng   +10 more
wiley   +1 more source

Open or closed: Experience of head and neck radiotherapy masks – A mixed‐methods study

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 74-84, March 2025.
Patients with head and neck cancer received radiotherapy alternately with an open and a closed mask. The closed mask was perceived as more confining and restrictive, but it was also considered to make it easier to quickly achieve the correct position, while the open mask was perceived as less stable, although it reduced the feeling of claustrophobia ...
Erik Lundin, Sofia Axelsson, Emma Ohlsson‐Nevo   +2 more
wiley   +1 more source

Racial and Ethnic Disparities in Facial Paralysis: Diagnosis, Comorbidities, and Chemodenervation

The Laryngoscope, EarlyView.
ABSTRACT Objectives Facial paralysis (FP) is associated with significant functional and psychosocial morbidity, yet potential racial and ethnic disparities in its diagnosis, associated comorbidities, and treatment patterns remain poorly characterized.
Amy Wang, Alexander J. Barna, Eric X. Wei, Scott J. Stephan, Priyesh N. Patel, Shiayin F. Yang   +5 more
wiley   +1 more source

Quality of Life in Children Who Are Deaf or Hard‐of‐Hearing and Their Families—A Scoping Review

The Laryngoscope, EarlyView.
This scoping review examines how quality of life is conceptualized and studied in young deaf and hard‐of‐hearing children and their families. The findings reveal inconsistent use of the term Quality of life, limiting cross‐study comparisons. Additionally, research is focused on children with cochlear implants while other groups remain underrepresented.
Nina Jakhelln Laugen, Evelien Dirks, Kerttu Huttunen   +2 more
wiley   +1 more source

Whole-Brain Radiotherapy [PDF]

, 2020
openaire   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Comparison of Coplanar and NonCoplanar VMAT Plans in HippocampusSparing Whole-Brain Radiotherapy

This study aimed to evaluate the effects of coplanar and non-coplanar treatment plans generated using the volumetric modulated arc therapy technique on hippocampal sparing and doses delivered to other critical organs in whole-brain radiotherapy ...
Volkan Avcı, Mustafa Çağlar, Ömer Yazıcı, Burcu Gerçek Kalyoncu, Özcan Özden, Celal Özbek Çakır, Burak Başlangıç, Murat Baloglu   +7 more
core   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Patient iPSC‐derived astrocytes reveal impaired homeostasis and reactive‐like features in propionic acidemia

The Journal of Pathology, EarlyView.
Abstract Propionic acidemia (PA) is a neurometabolic disorder caused by propionyl‐CoA carboxylase deficiency with frequent neurological involvement, yet cell‐type‐specific mechanisms remain poorly defined. We established human induced pluripotent stem cell (iPSC)‐derived astrocytes (iAs) from patients harboring PCCA or PCCB mutations and investigated ...
Irene González‐Garnacho, Mar Álvarez, Francisco Zafra, Pilar Rodríguez‐Pombo, Lourdes R Desviat, Eva Richard   +5 more
wiley   +1 more source