Results 161 to 170 of about 3,975,496 (251)

Peri‐operative management of patients having day surgery: a consensus statement from the Association of Anaesthetists, British Association for Day Surgery and the Association of Paediatric Anaesthetists, Great Britain and Ireland

open access: yesAnaesthesia, EarlyView.
Summary Introduction Day surgery is now recognised widely as being a vital component of modern healthcare delivery with overall day surgery rates in the UK now > 85%. Day surgery offers an enhanced experience for patients with reduced risk of postoperative complications (e.g.
Craig R. Bailey   +8 more
wiley   +1 more source

Reduced‐dose versus standard‐dose total body irradiation before allogeneic haematopoietic stem cell transplantation in adults with acute lymphoblastic leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Summary Comparative data on reduced‐dose (8 Gy) versus standard‐dose (12 Gy) total body irradiation (TBI) before allogeneic haematopoietic stem cell transplantation (allo‐HSCT) for adults with acute lymphoblastic leukaemia (ALL) remain limited. We retrospectively analysed 101 adults undergoing first allo‐HSCT between 1999 and 2024 after 8 Gy or 12 Gy ...
Isabella Gruber   +7 more
wiley   +1 more source

Cutis Verticis Gyrata in Association With Vemurafenib and Whole-Brain Radiotherapy [PDF]

open access: yesJournal of Clinical Oncology, 2014
James J, Harding   +5 more
openaire   +2 more sources

Sickle cell anaemia with and without crises: An observational study of pregnancy outcomes

open access: yesBritish Journal of Haematology, EarlyView.
Summary We assessed the pregnancy outcomes of patients with sickle cell crises. We carried out a retrospective study of 2 698 556 pregnancies in Quebec, Canada between 1989 and 2022. The primary exposure was sickle cell anaemia with crisis during or outside of pregnancy. Outcomes included severe maternal morbidity and other pregnancy complications.
Nathalie Auger   +8 more
wiley   +1 more source

Consensus recommendations on diagnosis and management of posterior reversible encephalopathy syndrome in paediatric haematopoietic stem cell transplantation

open access: yesBritish Journal of Haematology, EarlyView.
Summary Posterior reversible encephalopathy syndrome (PRES) is a rare but potentially life‐threatening neurological complication following paediatric allogeneic haematopoietic stem cell transplantation (HSCT). Its heterogeneous presentation and the absence of standardized guidance contribute to variability in diagnosis and management.
Davide Leardini   +25 more
wiley   +1 more source

Association of enlarged perivascular space burden with silent cerebral infarcts in children with sickle cell disease

open access: yesBritish Journal of Haematology, EarlyView.
Enlarged perivascular spaces (ePVS) in the basal ganglia and centrum semiovale are highly prevalent in children with sickle cell disease (SCD). Enlarged PVS in the basal ganglia are associated with the presence of silent cerebral infarcts, another marker of neurological disease, in children with SCD. Summary Children with sickle cell disease (SCD) have
Kristine A. Karkoska   +6 more
wiley   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

open access: yesBrain Pathology, EarlyView.
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar   +12 more
wiley   +1 more source

Complement receptor C3aR marks heterogeneous tumor‐associated macrophage states associated with improved survival in IDH‐wildtype glioblastoma

open access: yesBrain Pathology, EarlyView.
C3aR expression in IDH‐wildtype glioblastoma is predominantly associated with the myeloid/macrophage compartment and heterogeneous macrophage states. C3aR‐high tumors are enriched among MGMT promoter‐methylated tumors and show improved overall survival, although the prognostic association requires independent validation.
Marion Imara   +9 more
wiley   +1 more source

Molecular profiling of pediatric medulloblastoma in Kazakhstan: Genomic alterations, subgroup distribution, and survival

open access: yesBrain Pathology, EarlyView.
A practical formalin‐fixed, paraffin‐embedded (FFPE)‐based molecular workflow integrating pathology, immunohistochemistry, and genomic profiling provides clinically meaningful subgroup classification of pediatric medulloblastoma and expands molecular evidence from an underrepresented Central Asian population. Abstract Medulloblastoma is the most common
Aidos Bolatov   +9 more
wiley   +1 more source

Gliomas with pleomorphic and pseudopapillary features (GPAP) are circumscribed tumors with targetable mutations, prolonged survival, and frequent tumor predisposition

open access: yesBrain Pathology, EarlyView.
DNA methylation profiling identifies GPAP as a distinct circumscribed glioma with a characteristic expansive, multicystic radiological appearance, pleomorphic and pseudopapillary histology, a recognizable CNV profile, druggable molecular alterations, and recurrent cancer predisposition syndromes.
Alberto Picca   +35 more
wiley   +1 more source

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