Evidence for an ancient whole genome duplication in the cycad lineage. [PDF]
PLoS ONE, 2017 Contrary to the many whole genome duplication events recorded for angiosperms (flowering plants), whole genome duplications in gymnosperms (non-flowering seed plants) seem to be much rarer.
Danielle Roodt +5 more
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Interspecific introgression mediates adaptation to whole genome duplication [PDF]
Nature Communications, 2019 Whole genome duplication (WGD) presents new challenges to the establishment of optimal allelic combinations and to the meiotic machinery. Here, the authors show that adaptive gene flow from Arabidopsis arenosa could rescue the nascent A.
Sarah Marburger +9 more
doaj +4 more sources
Origin of the Yeast Whole-Genome Duplication.
PLoS Biology, 2015 Whole-genome duplications (WGDs) are rare evolutionary events with profound consequences. They double an organism's genetic content, immediately creating a reproductive barrier between it and its ancestors and providing raw material for the divergence of
Kenneth H Wolfe
doaj +4 more sources
ADARp150 counteracts whole genome duplication. [PDF]
Nucleic Acids ResAbstract Impaired control of the G1/S checkpoint allows initiation of DNA replication under non-permissive conditions. Unscheduled S-phase entry is associated with DNA replication stress, demanding for other checkpoints or cellular pathways to maintain proliferation.
van Gemert F +10 more
europepmc +5 more sources
Does hybridization between divergent progenitors drive whole-genome duplication? [PDF]
Molecular Ecology, 2009 This is the peer reviewed version of the following article: BUGGS, R. J. A., SOLTIS, P. S. and SOLTIS, D. E. (2009), Does hybridization between divergent progenitors drive whole-genome duplication?.
Buggs, RJA, Soltis, DE, Soltis, PS
core +4 more sources
Spontaneous whole-genome duplication restores fertility in interspecific hybrids [PDF]
Nature Communications, 2019 Hybridization across species can lead to offspring with reduced fertility. Here, the authors experimentally evolve yeast and show that whole-genome duplication during asexual reproduction can restore fertility in hybrids over a relatively short ...
Guillaume Charron +4 more
doaj +3 more sources
Ohno-miRNAs: miRNA pairs derived from whole-genome duplication. [PDF]
PLoS Computational BiologyTwo rounds of whole-genome duplication (WGD) occurred about 500 million years ago and played a major role in the evolution of the vertebrate genomes. Human genes derived from WGD are called "ohnologs".
Leonardo Agasso +2 more
doaj +2 more sources
GPCR genes are preferentially retained after whole genome duplication. [PDF]
PLoS ONE, 2008 One of the most interesting questions in biology is whether certain pathways have been favored during evolution, and if so, what properties could cause such a preference.
Jenia Semyonov +3 more
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The collapse of gene complement following whole genome duplication [PDF]
BMC Genomics, 2010 Background Genome amplification through duplication or proliferation of transposable elements has its counterpart in genome reduction, by elimination of DNA or by gene inactivation. Whether loss is primarily due to excision of random length DNA fragments
Zhu Qian, Zheng Chunfang, Sankoff David
doaj +4 more sources
Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer [PDF]
Nature CommunicationsWhole genome duplication is frequently observed in cancer, and its prevalence in our prior analysis of end-stage, homologous recombination deficient high grade serous ovarian cancer (almost 80% of samples) supports the notion that whole genome ...
Nikki L. Burdett +7 more
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