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Forensic Applications of Whole Genome Amplification [PDF]
, 2011 Whole genome amplification (WGA) has been touted as a possible technique to augment fragment analysis of STRs in amplifying low-levels of DNA recovered from crime scenes or items.
Williams, Graham
core +3 more sources
A model for biased fractionation after whole genome duplication [PDF]
BMC Genomics, 2012 Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion of multi-gene DNA segments is controversial, as is the question of fractionation bias, namely whether one homeologous chromosome is more vulnerable to gene deletion than the other.As a ...
David Sankoff +2 more
openaire +3 more sources
Mechanisms of gene duplication and translocation and progress towards understanding their relative contributions to animal genome evolution [PDF]
, 2012 Duplication of genetic material is clearly a major route to genetic change, with consequences for both evolution and disease. A variety of forms and mechanisms of duplication are recognised, operating across the scales of a few base pairs upto entire ...
Mendivil Ramos, Olivia +1 more
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Parallel evolution of amphioxus and vertebrate small-scale gene duplications
Genome Biology, 2022 Background Amphioxus are non-vertebrate chordates characterized by a slow morphological and molecular evolution. They share the basic chordate body-plan and genome organization with vertebrates but lack their 2R whole-genome duplications and their ...
Marina Brasó-Vives +13 more
doaj +1 more source
Genomic plasticity enables phenotypic variation of Pseudomonas syringae pv. tomato DC3000. [PDF]
PLoS ONE, 2014 Whole genome sequencing revealed the presence of a genomic anomaly in the region of 4.7 to 4.9 Mb of the Pseudomonas syringae pv. tomato (Pst) DC3000 genome.
Zhongmeng Bao +10 more
doaj +1 more source
Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region [PDF]
, 2012 Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functional
Gagneux, Sebastian +93 more
core +2 more sources
BMC Genomics, 2012 Background Gene duplication has had a major impact on genome evolution. Localized (or tandem) duplication resulting from unequal crossing over and whole genome duplication are believed to be the two dominant mechanisms contributing to vertebrate genome ...
Lu Jianguo +4 more
doaj +1 more source
The Impact of Whole Genome Duplication on the Evolution of the Arachnids
Integrative And Comparative Biology, 2023 Synopsis The proliferation of genomic resources for Chelicerata in the past 10 years has revealed that the evolution of chelicerate genomes is more dynamic than previously thought, with multiple waves of ancient whole genome duplications affecting separate lineages.
openaire +2 more sources
Inference of Ancient Whole-Genome Duplications and the Evolution of Gene Duplication and Loss Rates [PDF]
Molecular Biology and Evolution, 2019 Abstract Gene tree–species tree reconciliation methods have been employed for studying ancient whole-genome duplication (WGD) events across the eukaryotic tree of life. Most approaches have relied on using maximum likelihood trees and the maximum parsimony reconciliation thereof to count duplication events on specific branches of ...
Zwaenepoel, Arthur, Van de Peer, Yves
openaire +3 more sources
BMC Bioinformatics, 2022 Background Multiple processes impact the probability of retention of individual genes following whole genome duplication (WGD) events. In analyzing two consecutive whole genome duplication events that occurred in the lineage leading to Atlantic salmon, a
C. Nicholas Henry +6 more
doaj +1 more source